USP44

USP44
Identifiers
Aliases	USP44, ubiquitin specific peptidase 44
External IDs	OMIM: 610993 MGI: 3045318 HomoloGene: 12961 GeneCards: USP44
Gene location (Human)
Chr.	Chromosome 12 (human)[1]
End	95,551,476 bp[1]
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)[2]
End	93,858,088 bp[2]
RNA expression pattern
	More reference expression data
Gene ontology
Molecular function	• zinc ion binding; • peptidase activity; • cysteine-type peptidase activity; • GO:0001948 protein binding; • hydrolase activity; • metal ion binding; • thiol-dependent ubiquitin-specific protease activity;
Cellular component	• cell nucleus; • nucleoplasm; • cytoplasm;
Biological process	• cell cycle; • regulation of mitotic cell cycle spindle assembly checkpoint; • ubiquitin-dependent protein catabolic process; • proteasome-mediated ubiquitin-dependent protein catabolic process; • proteolysis; • cell division; • GO:0060564, GO:1904190 negative regulation of ubiquitin protein ligase activity; • protein deubiquitination; • chromosome segregation;
	Sources:Amigo / QuickGO
Orthologs
	84101
	327799
	ENSG00000136014
	ENSMUSG00000020020
	Q9H0E7
	Q8C2S0
	NM_001042403; NM_001278393; NM_032147; NM_001347936; NM_001347937
	NM_001206851; NM_183199; NM_001376981
	NP_001035862; NP_001265322; NP_115523; NP_001334865; NP_001334866
	NP_001193780; NP_001363910
	Wikidata
View/Edit Human	View/Edit Mouse

Ubiquitin carboxyl-terminal hydrolase 44 is an enzyme that in humans is encoded by the USP44 gene.[5][6]

References

GRCh38: Ensembl release 89: ENSG00000136014 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000020020 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Puente XS, Sanchez LM, Overall CM, Lopez-Otin C (Jul 2003). "Human and mouse proteases: a comparative genomic approach". Nat Rev Genet. 4 (7): 544–58. doi:10.1038/nrg1111. PMID 12838346. S2CID 2856065.
"Entrez Gene: USP44 ubiquitin specific peptidase 44".

Hartley JL, Temple GF, Brasch MA (2001). "DNA Cloning Using In Vitro Site-Specific Recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Quesada V, Díaz-Perales A, Gutiérrez-Fernández A, et al. (2004). "Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases". Biochem. Biophys. Res. Commun. 314 (1): 54–62. doi:10.1016/j.bbrc.2003.12.050. PMID 14715245.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to Biology: A Functional Genomics Pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
Stegmeier F, Rape M, Draviam VM, et al. (2007). "Anaphase initiation is regulated by antagonistic ubiquitination and deubiquitination activities". Nature. 446 (7138): 876–81. doi:10.1038/nature05694. PMID 17443180. S2CID 4321083.

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[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000136014 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000020020 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid12838346-5] Puente XS, Sanchez LM, Overall CM, Lopez-Otin C (Jul 2003). "Human and mouse proteases: a comparative genomic approach". Nat Rev Genet. 4 (7): 544–58. doi:10.1038/nrg1111. PMID 12838346. S2CID 2856065.

[entrez-6] "Entrez Gene: USP44 ubiquitin specific peptidase 44".

USP44

References

Further reading