USP5

Ubiquitin specific peptidase 5 is an enzyme that in humans is encoded by the USP5 gene.[5][6][7]

USP5
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesUSP5, ISOT, ubiquitin specific peptidase 5
External IDsOMIM: 601447 MGI: 1347343 HomoloGene: 55758 GeneCards: USP5
Gene location (Human)
Chr.Chromosome 12 (human)[1]
Band12p13.31Start6,852,128 bp[1]
End6,866,632 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

8078

22225

Ensembl

ENSG00000111667

ENSMUSG00000038429

UniProt

P45974

P56399

RefSeq (mRNA)

NM_001098536
NM_003481

NM_013700
NM_001326594

RefSeq (protein)

NP_001313523
NP_038728

Location (UCSC)Chr 12: 6.85 – 6.87 MbChr 6: 124.82 – 124.83 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

USP5 has been shown to interact with TADA3L.[8]

References

  1. GRCh38: Ensembl release 89: ENSG00000111667 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000038429 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Puente XS, Sánchez LM, Overall CM, López-Otín C (Jul 2003). "Human and mouse proteases: a comparative genomic approach". Nature Reviews Genetics. 4 (7): 544–58. doi:10.1038/nrg1111. PMID 12838346. S2CID 2856065.
  6. Ansari-Lari MA, Muzny DM, Lu J, Lu F, Lilley CE, Spanos S, Malley T, Gibbs RA (Apr 1996). "A gene-rich cluster between the CD4 and triosephosphate isomerase genes at human chromosome 12p13". Genome Research. 6 (4): 314–26. doi:10.1101/gr.6.4.314. PMID 8723724.
  7. "Entrez Gene: USP5 ubiquitin specific peptidase 5 (isopeptidase T)".
  8. Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (Oct 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.

Further reading


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