Vitamin A2

Vitamin A2 is a subcategory of Vitamin A which comprises several subforms like the major one vitamin A1 in the form of retinol, retinyl esters, retinal and provitamin A carotenoids, this vitamin A2, the likely non human relevant vitamin A3,4[1] and the newly postulated vitamin A5.[2]

Vitamin A2
Names
IUPAC name
(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexa-1,3-dien-1-yl)nona-2,4,6,8-tetraen-1-ol
Other names
Retinol 2
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.001.116
EC Number
  • 201-226-4
KEGG
UNII
Properties
C20H28O
Molar mass 284.443 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Dehydroretinal, more specifically, 3,4-dehydroretinal belongs to the group of vitamin A2 as a retinaldehyde form, besides the endogenously present 3,4-dehydroretinol (vitamin A2-alcohol) and 3,4-dehydroretinoic acid (vitamin A2 acid).[3][4]

References

  1. Babino D, Golczak M, Kiser PD, Wyss A, Placzewski K, von Lintig J (2016). "The Biochemical Basis of Vitamin A3 Production in Arthropod Vision". ACS Chem Biol. 11 (4): 1049–1057. doi:10.1021/acschembio.5b00967. PMC 4841470. PMID 26811964.
  2. Rühl R, Krężel W, de Lera AR (2018). "9-cis-13,14-Dihydroretinol, a new endogenous mammalian ligand of the retinoid X receptor and the active ligand of a potential new vitamin category: vitamin A5". Nutr. Rev. 76 (12): 929–941. doi:10.1093/nutrit/nuy057. PMID 30358857.
  3. Törmä H, Vahlquist A (1985). "Biosynthesis of 3-dehydroretinol (vitamin A2) from all-trans-retinol (vitamin A1) in human epidermis". J Invest Dermatol. 85 (6): 498–500. doi:10.1111/1523-1747.ep12277290. PMID 4067325.
  4. Vahlquist A (1980). "The identification of dehydroretinol (vitamin A2) in human skin". Experientia. 36 (3): 317–318. doi:10.1007/bf01952299. PMID 7371787. S2CID 31357743.
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