Voltage-gated potassium-channel Kv1.4 IRES

This family represents the Kv1.4 voltage-gated potassium channel internal ribosome entry site (IRES). This region has been shown to mediate internal ribosome entry in cells derived from brain, heart, and skeletal muscle; tissues known to express Kv1.4 mRNA species.[1]

Voltage-gated potassium-channel Kv1.4 IRES
Predicted secondary structure and sequence conservation of IRES_Kv1_4
Identifiers
SymbolIRES_Kv1_4
RfamRF00447
Other data
RNA typeCis-reg; IRES
Domain(s)Eukaryota
GOGO:0043022
SOSO:0000243
PDB structuresPDBe

References

  1. Jang GM, Leong LE, Hoang LT, Wang PH, Gutman GA, Semler BL (November 2004). "Structurally distinct elements mediate internal ribosome entry within the 5'-noncoding region of a voltage-gated potassium channel mRNA". The Journal of Biological Chemistry. 279 (46): 47419–47430. doi:10.1074/jbc.M405885200. PMID 15339906.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.