WDR45L

WD repeat domain phosphoinositide-interacting protein 3 (WIPI-3), also known as WD repeat-containing protein 45-like is a protein that in humans is encoded by the gene.[5]

WDR45B
Identifiers
AliasesWDR45B, WDR45L, WIPI-3, WIPI3, WD repeat domain 45B, NEDSBAS
External IDsOMIM: 609226 MGI: 1914090 HomoloGene: 6028 GeneCards: WDR45B
Gene location (Human)
Chr.Chromosome 17 (human)[1]
Band17q25.3Start82,614,562 bp[1]
End82,648,553 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

56270

66840

Ensembl

ENSG00000141580

ENSMUSG00000025173

UniProt

Q5MNZ6

Q9CR39

RefSeq (mRNA)

NM_019613

NM_025793

RefSeq (protein)

NP_062559

NP_080069

Location (UCSC)Chr 17: 82.61 – 82.65 MbChr 11: 121.33 – 121.35 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Structure and function

WIPI-3 is a member of the WIPI or SVP1 family of WD40 repeat-containing proteins. The protein contains seven WD40 repeats that are thought to fold into a beta-propeller structure that mediates protein–protein interactions, and a conserved motif for interaction with phospholipids.[5]

See also

References

  1. GRCh38: Ensembl release 89: ENSG00000141580 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000025173 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: WDR45-like".

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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