Walter Wahli

Prof. Walter Wahli is a Professor of Metabolic disease in Lee Kong Chian School of Medicine, a joint Medical School by Nanyang Technological University Singapore and Imperial College London.[2] He was awarded the Lifetime Achievement Award from the faculty of Biology and Medicine, at the University of Lausanne.[3]

Walter Wahli
Alma mater
Awards
  • Received Life Time Acheivement Award[1]
Scientific career
InstitutionsNanyang Technological University

Education

Prof. Dr. Walter Wahli was born on 23 May 1946 in Moutier, Switzerland. He studied Biological Sciences at the University of Bern in Switzerland; he earned his Ph.D. from the same university.[4]

Research and career

Prof. Dr. Walter Wahli's research mainly focuses on the Peroxisome proliferator-activated receptors (PPARs)[5] and he also did research on other nuclear receptors as positive and negative regulators of gene expression.[6] He investigated the role of PPARs in the most common liver disease known as Non-alcoholic fatty liver disease (NAFLD).[7] He underscored the potential of PPARs as drug targets for NAFLD that is often associated to Type 2 diabetes. Walter also did research on the PPARs as receptors exerting a nuclear control of energy metabolism.[8]

He is an Honorary Professor at the University of Lausanne (UNIL).[9] He is the Founder of the Center for Integrative Genomics (CIG) and currently serving at the Lee Kong Chian School of Medicine, a joint Medical School by Nanyang Technological University Singapore and Imperial College London as a Visiting Professor of Metabolic Disease.[10][11]

Prof. Dr. Walter Wahli obtained patents for his inventions. His patents include the Composition for regulating lipid metabolism (US8518459B2)[12] and the Composition for enhancing immunity (WO2014170505A3).[13]

Honors

Prof. Dr. Walter Wahli is one of the Advisory Board members of Imagene Labs, Singapore.[14] He served as a Scientific advisory board member of an International Cancer Prevention Institute.[15] He was a member of the Swiss National Science Foundation research council and presided over the Biology and Medicine Division.[16] His Editorial Memberships include, among others, the Open Nutrition Journal,[17] Journal of Steroid Biochemistry and Molecular Biology[18] and Editorial board member of Cell & Bioscience.[19]

Dr. Walter Wahli won the Otto-Naegeli-Preis Award for his medical research in the field of Cell Biology/Energy homeostasis. Additional awards include the European Federation of Lipid research Award[20] and Lifetime Achievement Award from the University of Lausanne.[21] He was appointed as a Pierre De Fermat Chair of Excellence at Midi-Pyrenees research Centre, Toulouse.[22] He is a Guest Editor of International Journal of Molecular sciences.[23]

Publications
  • Peroxisome proliferator-activated receptors: nuclear control of metabolism.[24]
  • Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha,-beta, and-gamma in the adult rat.[25]
  • Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors α and γ.[26]
  • Roles of PPARs in health and disease.[27]
  • Peroxisome proliferator–activated receptor α mediates the adaptive response to fasting.[28]

References
  1. "Walter". genomyx.ch.
  2. "Walter Wahli | Metabolomics Congress 2017 | Conferenceseries". www.metabolomicsconference.com. Retrieved 2019-10-24.
  3. "FBM Awardees 2011". www.genomyx.ch. Retrieved 2019-10-24.
  4. "Prof. Dr. Walter Wahli". www.swir.ch. Retrieved 2019-10-24.
  5. Wahli, Walter (2002). "Peroxisome proliferator-activated receptors (PPARs): from metabolic control to epidermal wound healing". Swiss Medical Weekly. 132 (7–8): 83–91. doi:10.4414/smw.2002.09939 (inactive 2021-01-14). ISSN 1424-7860. PMID 11971202. Retrieved 2019-10-27.CS1 maint: DOI inactive as of January 2021 (link)
  6. Wahli, W; Martinez, E (1991-06-01). "Superfamily of steroid nuclear receptors: positive and negative regulators of gene expression". The FASEB Journal. 5 (9): 2243–2249. doi:10.1096/fasebj.5.9.1860615. ISSN 0892-6638. PMID 1860615. S2CID 1464261.
  7. Chen, Jiapeng; Montagner, Alexandra; Tan, Nguan Soon; Wahli, Walter (2018). "Insights into the Role of PPARß/d in NAFLD". International Journal of Molecular Sciences. 19 (7): 1893. doi:10.3390/ijms19071893. PMC 6073272. PMID 29954129.
  8. Desvergne, Béatrice; Wahli, Walter (1999-10-01). "Peroxisome Proliferator-Activated Receptors: Nuclear Control of Metabolism". Endocrine Reviews. 20 (5): 649–688. doi:10.1210/edrv.20.5.0380. ISSN 0163-769X. PMID 10529898.
  9. "Unisciences - UNIL - Walter Wahli". applicationspub.unil.ch. Retrieved 2019-10-24.
  10. "About". www.unil.ch. Retrieved 2019-10-24.
  11. "Prof. Wahli". www.unil.ch. Retrieved 2019-10-24.
  12. , "Composition for regulating lipid metabolism", issued 2010-04-15
  13. , "Composition for enhancing immunity", issued 2014-04-22
  14. "DNA Tests for Personalized Beauty, Health & Wellness | Imagene Labs". Retrieved 2019-10-24.
  15. "ICPI website" (PDF).
  16. "Prof. Dr. Walter Wahli". www.swir.ch. Retrieved 2019-10-24.
  17. "The Open Nutrition Journal - Editorial Board". opennutritionjournal.com. Retrieved 2019-10-24.
  18. The Journal of Steroid Biochemistry and Molecular Biology Editorial Board.
  19. "Cell & Bioscience". Cell & Bioscience. Retrieved 2019-10-24.
  20. "Prof. Wahli". www.unil.ch. Retrieved 2019-10-24.
  21. "FBM Awardees 2011". www.genomyx.ch. Retrieved 2019-10-24.
  22. "toulouse infra".
  23. "International Journal of Molecular Sciences". www.mdpi.com. Retrieved 2019-10-24.
  24. Desvergne, B.; Wahli, W. (1999). "Peroxisome proliferator-activated receptors: nuclear control of metabolism". Endocrine Reviews. 20 (5): 649–688. doi:10.1210/edrv.20.5.0380. ISSN 0163-769X. PMID 10529898.
  25. Braissant, O.; Foufelle, F.; Scotto, C.; Dauça, M.; Wahli, W. (1996-01-01). "Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat". Endocrinology. 137 (1): 354–366. doi:10.1210/endo.137.1.8536636. ISSN 0013-7227. PMID 8536636.
  26. Kliewer, Steven A.; Sundseth, Scott S.; Jones, Stacey A.; Brown, Peter J.; Wisely, G. Bruce; Koble, Cecilia S.; Devchand, Pallavi; Wahli, Walter; Willson, Timothy M.; Lenhard, James M.; Lehmann, Jürgen M. (1997-04-29). "Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors α and γ". Proceedings of the National Academy of Sciences. 94 (9): 4318–4323. Bibcode:1997PNAS...94.4318K. doi:10.1073/pnas.94.9.4318. ISSN 0027-8424. PMC 20720. PMID 9113987.
  27. Kersten, Sander; Desvergne, Béatrice; Wahli, Walter (2000). "Roles of PPARs in health and disease". Nature. 405 (6785): 421–424. Bibcode:2000Natur.405..421K. doi:10.1038/35013000. ISSN 1476-4687. PMID 10839530. S2CID 4373446.
  28. Kersten, Sander; Seydoux, Josiane; Peters, Jeffrey M.; Gonzalez, Frank J.; Desvergne, Béatrice; Wahli, Walter (1999-06-01). "Peroxisome proliferator–activated receptor α mediates the adaptive response to fasting". The Journal of Clinical Investigation. 103 (11): 1489–1498. doi:10.1172/JCI6223. ISSN 0021-9738. PMC 408372. PMID 10359558.
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