What's with Andy?

Andy is a teenager who loves to prank people as well as annoy his friends and family (especially his sister), but often gets into trouble. His best friend is Danny and he has a crush on Lori. His catchphrase is "Check, please!".

The best friend and Andy's right-hand man, helping him out with countless pranks. His last name has always been Pickett. The name "Danny Pickett" is derived from Jim Kjelgaard's Big Red.

Andy's crush but she is dismayed by his childishness due to his pranking. It is hinted that she returns Andy's feelings and dislikes Jen because Lori thinks that Jen abuses Andy. She wears a green tank top, blue skirt and sandals. She is known as "Lisa" in the books.

• Mr. Larkin: Andy and Jen's father and Freida's husband who also used to be a prankster, known as "The Mystery Prankster", aka "The Mystery Prankster of East Gackle" (he hides this fact from his family). However, he was cured of pranking by school counselor, Mrs. Murphy.
• Mrs. Larkin: Andy and Jen's mother and Al's wife. She knows nothing about her husband's past as a prankster.
• Jen Larkin: Andy's older sister who is always cranky and irritable. She blames her younger brother Andy for almost everything and finds his pranks childish and unfunny. She is unaware of her father's past as a prankster.
• Spank Larkin: Andy's fat and lazy dog. Spank frequently yawns, especially after going for a walk. He also appears to have flatulence problems.
• Norman Larkin:

• Teri: Jen's best friend.
• Jervis Coltrane: A French snob who has a crush on Lori Mackney and dreams of being the Prime Minister of Canada.
• Peter Lik and Andrew Leech: Peter and Andrew are Andy's and Danny's nemeses. They are usually referred to as Lik and Leech.
• Craig Bennett: Jen's crush and one of the best athletes of East Gackle.
• Martin Bonwick: He is a stereotypically nervous nerd who very often gets bullied.
• Victor "Vic" Muskowitz (Mush): The pizza delivery man of East Gackle who is a good friend of Andy and Danny and he sometimes helps them with pranks.
• Steve Rowgee Jr.: A dumb police officer who is the incompetent son of Steve Rowgee Sr.
• Steve Rowgee Sr.: A police officer who is an old man, who always commands Steve Rowgee Jr. (his son) and is nicknamed the Iron Fisted Maniac.
• Principal DeRosa: He is the bad-tempered principal of the school in East Gackle and the main antagonist who is obsessed with punishing Andy.
• Mr. Hutchins: One of the many teachers at East Gackle school, Andy likes to prank him more than the other teachers.
• Mayor Henry K. Roth: The mayor of East Gackle.
• Mayor Simms: Mayor of West Gackle and Mayor Henry K. Roth's rival.
• Clyde: The janitor of the school.
• Hazel Strinner: She has a crush on Andy and Lori's protecting friend.
• Louella Berman: Frieda's best friend.
• Mrs. Wibbles: Principal DeRosa's secretary.

• Jodi Carlisle
• Tim Conway
• E. G. Daily
• Melissa Disney
• Jeannie Elias
• Barbara Goodson
• Melissa Greenspan
• Jess Harnell
• Maurice LaMarche
• André Sogliuzzo
• Kath Soucie
• Jim Ward

What's with Andy? originally aired on Teletoon in Canada.[9] In Australia, where the books originated, it was broadcast on Fox Kids.[10]

In the United States, the series was first shown on September 22, 2001[11][12] on Fox Family Channel,[13] later ABC Family.[14] On January 17, 2005, it premiered on Toon Disney, which also aired the second and third seasons.[15]

In Europe, the show aired on Fox Kids,[16] later known as Jetix.[17] In France, it was also broadcast on TF1,[18] while in Germany it aired on Super RTL.[19]

In Canada, three VHS volumes were released by CinéGroupe/Star on April 8, 2003[20] in both English[21][22][23] and French, containing episodes 10, 1, and 4 respectively.[24][25][26] Each also includes an episode of The Kids from Room 402 and a music video from the Pig City soundtrack.

All 26 episodes from season 1, as well as the first 7 episodes of season 2, were released on 10 DVD volumes with English audio in the Czech Republic in 2010.[27][28]

The show was also released on DVD in other European countries, but only in the respective languages (i.e. without the original English audio). All of season 2 (and most of season 1) was released on DVD in Germany,[29] and the entirety of season 1 was released on 5 DVD volumes in Russia.[30]