Zinc finger protein 674

ZNF674
Identifiers
Aliases	ZNF674, MRX92, ZNF673B, zinc finger protein 674
External IDs	OMIM: 300573 HomoloGene: 87837 GeneCards: ZNF674
Gene location (Human)
Chr.	X chromosome (human)[1]
End	46,545,457 bp[1]
Gene ontology
Molecular function	• DNA binding; • metal ion binding; • nucleic acid binding; • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	• intracellular; • cell nucleus;
Biological process	• regulation of transcription, DNA-templated; • transcription, DNA-templated; • regulation of transcription from RNA polymerase II promoter; • negative regulation of transcription, DNA-templated;
	Sources:Amigo / QuickGO
Orthologs
	641339
	n/a
	ENSG00000251192
	n/a
	Q2M3X9
	n/a
	NM_001039891; NM_001146291; NM_001190417
	n/a
	NP_001034980; NP_001139763; NP_001177346
	n/a
	Wikidata
View/Edit Human

Zinc finger protein 674 is a protein that in humans is encoded by the ZNF674 gene. [3]

Function

This gene encodes a zinc finger protein with an N-terminal Kruppel-associated box-containing (KRAB) domain and 11 Kruppel-type C2H2 zinc finger domains. Like other zinc finger proteins, this gene may function as a transcription factor. This gene resides on an area of chromosome X that has been implicated in nonsyndromic X-linked mental retardation. Alternative splicing results in multiple transcript variants encoding different isoforms.

GRCh38: Ensembl release 89: ENSG00000251192 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Entrez Gene: Zinc finger protein 674". Retrieved 2016-03-02.