23S rRNA pseudouridine2605 synthase

23S rRNA pseudouridine2605 synthase (EC 5.4.99.22, RluB, YciL) is an enzyme with systematic name 23S rRNA-uridine2605 uracil mutase.[1][2] This enzyme catalyses the following chemical reaction

23S rRNA uridine2605 23S rRNA pseudouridine2605
23S rRNA pseudouridine2605 synthase
Identifiers
EC number5.4.99.22
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

Pseudouridine synthase RluB converts uridine2605 of 23S rRNA to pseudouridine.

References

  1. Del Campo M, Kaya Y, Ofengand J (November 2001). "Identification and site of action of the remaining four putative pseudouridine synthases in Escherichia coli". RNA. 7 (11): 1603–15. PMC 1370202. PMID 11720289.
  2. Jiang M, Sullivan SM, Walker AK, Strahler JR, Andrews PC, Maddock JR (May 2007). "Identification of novel Escherichia coli ribosome-associated proteins using isobaric tags and multidimensional protein identification techniques". Journal of Bacteriology. 189 (9): 3434–44. doi:10.1128/jb.00090-07. PMC 1855874. PMID 17337586.
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