3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate dehydrogenase
3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate dehydrogenase (EC 1.3.1.87, hcaB (gene), cis-dihydrodiol dehydrogenase, 2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase) is an enzyme with systematic name 3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate:NAD+ oxidoreductase.[1] This enzyme catalyses the following chemical reaction
- (1) 3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate + NAD+ 3-(2,3-dihydroxyphenyl)propanoate + NADH + H+
- (2) (2E)-3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)prop-2-enoate + NAD+ (2E)-3-(2,3-dihydroxyphenyl)prop-2-enoate + NADH + H+
| 3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate dehydrogenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.3.1.87 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
This enzyme catalyses a step in indegradation of phenylpropanoid compounds.
References
- Díaz E, Ferrández A, García JL (June 1998). "Characterization of the hca cluster encoding the dioxygenolytic pathway for initial catabolism of 3-phenylpropionic acid in Escherichia coli K-12". Journal of Bacteriology. 180 (11): 2915–23. PMC 107259. PMID 9603882.
External links
- 3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate+dehydrogenase at the US National Library of Medicine Medical Subject Headings (MeSH)
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