4-Phenyl-4-(1-piperidinyl)cyclohexanol

4-Phenyl-4-(1-piperidinyl)cyclohexanol
Names
	Preferred IUPAC name 4-Phenyl-4-(piperidin-1-yl)cyclohexan-1-ol
	Other names 4-Phenyl-4-(1-piperidinyl)cyclohexanol
Identifiers
CAS Number	60756-83-4 ;
3D model (JSmol)	Interactive image; Interactive image;
ChemSpider	142418 ;
PubChem CID	162171;
UNII	TAJ3PEY6RN ;
CompTox Dashboard (EPA)	DTXSID60209577 ;
	InChI InChI=1S/C17H25NO/c19-16-9-11-17(12-10-16,15-7-3-1-4-8-15)18-13-5-2-6-14-18/h1,3-4,7-8,16,19H,2,5-6,9-14H2 Key: KPRUAZBLIREHPD-UHFFFAOYSA-N ; InChI=1/C17H25NO/c19-16-9-11-17(12-10-16,15-7-3-1-4-8-15)18-13-5-2-6-14-18/h1,3-4,7-8,16,19H,2,5-6,9-14H2 Key: KPRUAZBLIREHPD-UHFFFAOYAM;
	SMILES OC1CCC(N2CCCCC2)(C3=CC=CC=C3)CC1; OC3CCC(c1ccccc1)(N2CCCCC2)CC3;
Properties
Chemical formula	C17H25NO
Molar mass	259.391 g/mol
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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	Infobox references

4-Phenyl-4-(1-piperidinyl)cyclohexanol, also known as PPC, is an organic chemical which is a metabolite of phencyclidine (PCP).[1] It can be detected in the hair of PCP users.[2]

PPC has been shown to cause increases in locomotor activity in lab mice.[3]

References

Nabeshima, Toshitaka; Yamaguchi, Kazumasa; Fukaya, Hiroaki; Hiramatsu, Masayuki; Furukawa, Hiroshi; Kameyama, Tsutomu (1985). "Simultaneous determination of phencyclidine and its major metabolites in biological samples by high-performance liquid chromatography". Research Communications in Substances of Abuse. 6 (2): 65–78.
Nakahara, Yuji; Takahashi, Kazunori; Sakamoto, Tomoaki; Tanaka, Akira; Hill, Virginia A.; Baumgartner, Werner A. (1997). "Hair analysis for drugs of abuse XVII. Simultaneous detection of PCP, PCHP, and PCPdiol in human hair for confirmation of PCP use". Journal of Analytical Toxicology. 21 (5): 356–362. doi:10.1093/jat/21.5.356. PMID 9288587.
"Behavioral effects of phencyclidine and its major metabolite, (trans)4-phenyl-4-(1-piperidinyl)cyclohexanol, in mice".

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[1] Nabeshima, Toshitaka; Yamaguchi, Kazumasa; Fukaya, Hiroaki; Hiramatsu, Masayuki; Furukawa, Hiroshi; Kameyama, Tsutomu (1985). "Simultaneous determination of phencyclidine and its major metabolites in biological samples by high-performance liquid chromatography". Research Communications in Substances of Abuse. 6 (2): 65–78.

[2] Nakahara, Yuji; Takahashi, Kazunori; Sakamoto, Tomoaki; Tanaka, Akira; Hill, Virginia A.; Baumgartner, Werner A. (1997). "Hair analysis for drugs of abuse XVII. Simultaneous detection of PCP, PCHP, and PCPdiol in human hair for confirmation of PCP use". Journal of Analytical Toxicology. 21 (5): 356–362. doi:10.1093/jat/21.5.356. PMID 9288587.

[3] "Behavioral effects of phencyclidine and its major metabolite, (trans)4-phenyl-4-(1-piperidinyl)cyclohexanol, in mice".

4-Phenyl-4-(1-piperidinyl)cyclohexanol

See also

References