ACYP1

Acylphosphatase-1 is an enzyme that in humans is encoded by the ACYP1 gene.[5][6][7]

ACYP1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesACYP1, ACYPE, acylphosphatase 1
External IDsOMIM: 600875 MGI: 1913454 HomoloGene: 11932 GeneCards: ACYP1
Gene location (Human)
Chr.Chromosome 14 (human)[1]
Band14q24.3Start75,053,237 bp[1]
End75,069,483 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

97

66204

Ensembl

ENSG00000119640

ENSMUSG00000008822

UniProt

P07311

P56376

RefSeq (mRNA)

NM_001107
NM_001302616
NM_001302617
NM_203488

NM_025421
NM_001364360
NM_001364361

RefSeq (protein)

NP_001098
NP_001289545
NP_001289546

NP_079697
NP_001351289
NP_001351290

Location (UCSC)Chr 14: 75.05 – 75.07 MbChr 12: 85.27 – 85.29 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

Acylphosphatase is a small cytosolic enzyme that catalyzes the hydrolysis of the carboxyl-phosphate bond of acylphosphates. Two isoenzymes have been isolated, called muscle acylphosphatase and erythrocyte acylphosphatase, on the basis of their tissue localization. This gene encodes the erythrocyte acylphosphatase isoenzyme. Alternatively spliced transcript variants that encode different proteins were identified through data analysis.[7]

References

  1. GRCh38: Ensembl release 89: ENSG00000119640 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000008822 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Fiaschi T, Raugei G, Marzocchini R, Chiarugi P, Cirri P, Ramponi G (Jun 1995). "Cloning and expression of the cDNA coding for the erythrocyte isoenzyme of human acylphosphatase". FEBS Letters. 367 (2): 145–8. doi:10.1016/0014-5793(95)00553-L. PMID 7796909.
  6. Fiaschi T, Marzella R, Veggi D, Marzocchini R, Raugei G, Rocchi M, Ramponi G (Oct 1998). "Assignment of the human erythrocyte acylphosphatase gene (ACYP1) to chromosome band 14q24.3". Cytogenetics and Cell Genetics. 81 (3–4): 235–6. doi:10.1159/000015037. PMID 9730610.
  7. "Entrez Gene: ACYP1 acylphosphatase 1, erythrocyte (common) type".

Further reading

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