Alkenylglycerophosphoethanolamine hydrolase

In enzymology, an alkenylglycerophosphoethanolamine hydrolase (EC 3.3.2.5) is an enzyme that catalyzes the chemical reaction

1-(1-alkenyl)-sn-glycero-3-phosphoethanolamine + H2O an aldehyde + sn-glycero-3-phosphoethanolamine
alkenylglycerophosphoethanolamine hydrolase
Identifiers
EC number3.3.2.5
CAS number78413-08-8
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

Thus, the two substrates of this enzyme are 1-(1-alkenyl)-sn-glycero-3-phosphoethanolamine and H2O, whereas its two products are aldehyde and sn-glycero-3-phosphoethanolamine.

This enzyme belongs to the family of hydrolases, specifically those acting on ether bonds (ether hydrolases). The systematic name of this enzyme class is 1-(1-alkenyl)-sn-glycero-3-phosphoethanolamine aldehydohydrolase. This enzyme participates in ether lipid metabolism.

References

    • Gunawan J, Debuch H (1981). "Liberation of free aldehyde from 1-(1-alkenyl)-sn-glycero-3-phosphoethanolamine (lysoplasmalogen) by rat liver microsomes". Hoppe-Seyler's Z. Physiol. Chem. 362 (4): 445–52. doi:10.1515/bchm2.1981.362.1.445. PMID 7239443.


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