Alkylphosphocholine

Alkylphosphocholines are phospholipid-like molecules that have been synthesised, which have remarkable biological and therapeutic activities.[1][2] They are phosphocholine esters of aliphatic long chain alcohols differing in chain length, unsaturation and position of the cis-double bond.[3]

References
  1. Unger C, Sindermann H, Peukert M, Hilgard P, Engel J, Eibl H (1992). "Hexadecylphosphocholine in the topical treatment of skin metastases in breast cancer patients". Progress in Experimental Tumor Research. Fortschritte der Experimentellen Tumorforschung. Progrès de la Recherche Expérimentale des Tumeurs. Progress in Tumor Research. 34: 153–9. doi:10.1159/000420840. ISBN 978-3-8055-5464-0. PMID 1438798.
  2. Zeisig R, Jungmann S, Fichtner I, Daemen T, Arndt D (1994). "Cytotoxic effects of alkylphosphocholines or alkylphosphocholine-liposomes and macrophages on tumor cells". Anticancer Research. 14 (5A): 1785–9. PMID 7847811.
  3. Dietrich Arndt; Reiner Zeisig; Ines Eue & Iduna Fichtner (1995). "Alkylphosphocholines and Alkylphosphocholine Liposomes". Journal of Liposome Research. 5 (1): 91–98. doi:10.3109/08982109509039910.


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