Angela Gronenborn

Angela Gronenborn FRSC is the head of the Department of Structural Biology at the University of Pittsburgh School of Medicine and the holder of the UPMC Rosalind Franklin Chair. She specializes in the use of NMR spectroscopy to study proteins and macromolecular complexes. Her work has focused on the study of proteins involved in human immunodeficiency virus (HIV) replication and she directs the Pittsburgh Center for HIV Protein Interactions.[1]

Angela M. Gronenborn
Born (1950-05-11) May 11, 1950
Cologne, Germany
NationalityGerman
CitizenshipGermany and United States
Alma materUniversity of Cologne
Known forBiomolecular nuclear magnetic resonance
AwardsMember of the United States National Academy of Sciences
Fellow of the American Academy of Arts and Sciences
Scientific career
Fieldsstructural biology, nuclear magnetic resonance
InstitutionsUniversity of Pittsburgh School of Medicine
Doctoral advisorHarald Günter

Career

A native of Cologne, Germany, Gronenborn received her undergraduate degree in 1975 and her Ph.D. in physical chemistry in 1978, both from the University of Cologne. During her graduate work she became interested in the then-young field of nuclear magnetic resonance spectroscopy applied to biological macromolecules. She did postdoctoral work with protein NMR pioneer James Feeney at the National Institute for Medical Research in London, where she met fellow spectroscopist and longtime collaborator Marius Clore.[2]

Clore and Gronennborn moved in 1984 to the Max Planck Institute and in 1988 to the National Institute of Diabetes and Digestive and Kidney Diseases, part of the United States National Institutes of Health, to which they were recruited in part to assist efforts in studying HIV and HIV-related proteins. Gronenborn and [2]Clore, along with Ad Bax and Dennis Torchia, made significant advances in three-dimensional protein NMR during this period.[3][4] Gronenborn held the position of Section Chief of Structural Biology from 1991-2005.

In 2004 Gronenborn moved to the University of Pittsburgh School of Medicine to head its department of structural biology, while also holding professorships in both the Department of Pharmacology and the Department of Bioengineering, where she has remained since.[1][2] She has published over 500 times throughout her career.

Awards and memberships

Gronenborn is a Fellow of the Royal Society of Chemistry U.K., the American Association for the Advancement of Science.[1]

  • Elected to the United States National Academy of Sciences (2007)
  • Elected Fellow of the International Society of Magnetic Resonance (2008)
  • Elected to the Norwegian Academy of Science and Letters (2010)
  • Einstein Visiting Fellow, Berlin, Germany (2015-2018)
  • President of the Biophysical Society (2018-2019)
  • Elected to the American Academy of Arts and Science (2018)
  • Mildred Cohn Award in Biological Chemistry (2019)
  • Richard R. Ernst Prize in Magnetic Resonance (2019)
  • E. Bright Wilson Award in Spectroscopy (2020)

References
  1. "Angela M. Gronenborn". University of Pittsburgh, Department of Structural Biology. Archived from the original on 2 April 2015. Retrieved 13 March 2015.
  2. Katznelson, Alla. "Great Expectations". Pitt Med (Winter 2014). University of Pittsburgh School of Medicine. Retrieved 13 March 2015.
  3. Clore, G Marius (2011). "Adventures in Biomolecular NMR" (PDF). In Harris, Robin K; Wasylishen, Roderick L (eds.). Encyclopedia of Magnetic Resonance. John Wiley & Sons. doi:10.1002/9780470034590. hdl:11693/53364. ISBN 9780470034590.
  4. "PDB Community Focus: Angela Gronenborn, University of Pittsburgh". RCSB PDB Newsletter (33). Research Collaboratory for Structural Bioinformatics. Spring 2007. Retrieved 13 March 2015.
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