Autologous stem-cell transplantation

Autologous stem-cell transplantation (also called autogenous, autogeneic, or autogenic stem-cell transplantation and abbreviated auto-SCT) is autologous transplantation of stem cells[1]—that is, transplantation in which stem cells (undifferentiated cells from which other cell types develop) are removed from a person, stored, and later given back to that same person.[2][3]

Although it is most frequently performed with hematopoietic stem cells (precursors of blood-forming cells) in hematopoietic stem cell transplantation, cardiac cells have also been used successfully to repair damage caused by heart attacks.[4]

Autologous stem-cell transplantation is distinguished from allogenic stem cell transplantation where the donor and the recipient of the stem cells are different people.

See also

References
  1. "What Are Stem Cells?". Retrieved 2017-02-12.
  2. Mahla RS (2016). "Stem cells application in regenerative medicine and disease threpeutics". International Journal of Cell Biology. 2016 (7): 19. doi:10.1155/2016/6940283. PMC 4969512. PMID 27516776.CS1 maint: uses authors parameter (link)
  3. "Autologous (Self) Transplants". The Leukaemia Foundation. The Leukaemia Foundation. Retrieved 27 September 2017.
  4. Stamm, Christof; Westphal, Bernd; Kleine, Hans-Dieter; Petzsch, Michael; Kittner, Christian; Klinge, Heiko; Schümichen, Carl; Nienaber, Christoph A; Freund, Mathias (2003-01-04). "Autologous bone-marrow stem-cell transplantation for myocardial regeneration". The Lancet. 361 (9351): 45–46. doi:10.1016/S0140-6736(03)12110-1. PMID 12517467.
  • Autologous stem-cell transplantation entry in the public domain NCI Dictionary of Cancer Terms
  • ScienceDaily Report University of Louisville. "Two years out, patients receiving stem cell therapy show sustained heart function improvement, study suggests." ScienceDaily, 6 Nov. 2012. Web. 6 Nov. 2012.


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