Bicinchoninic acid

Bicinchoninic acid /bsɪnkɔːnɪnɪk/ is a weak acid composed of two carboxylated quinoline rings.

Bicinchoninic acid
Names
Preferred IUPAC name
[2,2'-Biquinoline]-4,4'-dicarboxylic acid
Other names
Bicinchoninic acid
4,4'-Dicarboxy-2,2'-biquinoline
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.013.628
UNII
Properties
C20H12N2O4
Molar mass 344.326 g·mol−1
Appearance Cream colored powder
Odor Characteristic odor
Melting point 365 to 367 °C (689 to 693 °F; 638 to 640 K)
Partially soluble in cold water, hot water
Hazards
Main hazards Will irritate eyes and mucous membranes.
Safety data sheet External MSDS
NFPA 704 (fire diamond)
Flammability (red): no hazard codeHealth code 1: Exposure would cause irritation but only minor residual injury. E.g. turpentineReactivity (yellow): no hazard codeSpecial hazards (white): no code
1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Bicinchoninic acid is most commonly employed by biochemists in the bicinchoninic acid (BCA) assay, which is used to determine the total level of protein in a solution. In this assay, two molecules of bicinchoninic acid chelate a single Cu+ ion, forming a purple water-soluble complex that strongly absorbs light at 562 nm.[1]

References

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