Celebrity Deathmatch

• Johnny Gomez (Maurice Schlafer, 1998–2002), (Jim Thornton, 2006-07): One of the two joint commentators on the Celebrity Deathmatches, Johnny is the more professional one, and a loyal friend of Nick's despite his constant blunders. He only lost his professionalism once to Lenny Stanton, the producer's son and nearly lost it a second time concerning interviewer Tally Wong. Johnny's hair has noticeably changed from black to brown in the new season. Judging by a comment made by Tally during one episode, he may be wearing a hairpiece. Johnny harbors an intense hatred for her akin to Nick and Debbie, but tries to maintain being a professional. He was born in Illinois. Johnny would often end the episodes with his catchphrase "good fight, good night". Johnny bears a striking resemblance to Mike Adamle, former professional football player and sports announcer, who was a host and an announcer for American Gladiators.
• Nick Diamond (Len Maxwell, 1998–2002), (Chris Edgerly, 2006-07): Johnny Gomez's co-host, a perceived alcoholic and divorced father of one, he is always screwing up. He harbors an intense hatred for interviewer Debbie Matenopoulos, and has also participated in, and won, several matches by himself. Nick is apparently so hopeless that when he mentions having an uneventful weekend, Johnny spends the show preparing for the inevitable disaster to befall his co-commentator. He was born in Virginia. Nick bears a striking resemblance to Larry Csonka, former college and pro football hall of famer, who was one of the hosts and announcers on American Gladiators.
• Mills Lane (himself, 1998–2002), (Chris Edgerly, 2006-07): The official referee of the Deathmatch ring; he always starts matches by saying "Let's get it on!" and shows that this is one referee that cannot be knocked down with one hit. Another catch phrase is when there is a disputable move by either fighter, like using foreign objects, and he says "I'll allow it!" implying that just about anything is legal in the ring. Biting and guns are his only reservation as well as having a dirty fighting ring.[9] After he suffered a stroke in 2002, the real Mills stopped providing the voice of his own character but gave Edgerly his blessing.
• Stone Cold Steve Austin (himself): World Wrestling Entertainment (WWE) wrestler and guest commentator on Celebrity Deathmatch. Also the scientist, doctor and weapons expert on the show. He also fought and won a match against Vince McMahon (voiced by McMahon himself, and whom Austin would actually wrestle with on several WWE events in real life). Austin did not show up in the later seasons, for Nick has once stated that he was too expensive to bring back.
• Stacey Cornbred, (Becca Lish): The first interviewer on Celebrity Deathmatch, Stacey maintained a more professional air than Tally, Debbie and Marv. She kept her interviewing job until her untimely demise from spontaneous human combustion. Though she had exploded, she briefly returned in a Halloween episode as a zombie to challenge Debbie in the ring only to be soundly (and messily) defeated.
• Debbie Matenopoulos (herself): The interviewer that succeeded Stacey Cornbred after her death. She hates Nick and does not prepare for any interviews, usually just asking whatever she feels like. Debbie often believes herself to be smarter than she really is, but is really self-centered and unprofessional. She left the show late in the 4th season on maternity leave. Debbie is similar to Tally in the way they act and behave during interviews.
• Tally Wong (Masasa Moyo): The new interviewer from Season 5 onward. Before most of the matches, she interviews the combatants in a segment called "Tally's Korner". Like Debbie, Tally is very self-centered and unprofessional. She usually spends most of her interviews insulting the celebrities rather than asking questions. The only time Tally does ask questions, she often asks whatever she feels like asking and when they refuse to answer, she makes rude remarks about them. At times, she makes rude remarks about Nick and Johnny during matches, earning her their ire, including making remarks about them wearing hairpieces. Whenever Nick or Johnny gets mad at her for it, she taunts them by daring them to "bring back Stacey Cornbred." Tally harbors an intense hatred toward Johnny Gomez, which proves to be mutual. Ironically though, this was the inverse in the previous show with Nick Diamond hating on Debbie Matenopoulos.
• Marv Albert (Buck Lee): CDM's first guest commentator. He only appeared in the pilot episode and was best recognized for wasting the whole show watching the slow-motion replay of Pamela Anderson's implant-laden breasts jiggling repeatedly. Because of this, Johnny and Nick had Marv replaced with the more professional Stacey Cornbred until her untimely death.
• Phil the popcorn guy (Jim Conroy): A running gag; usually among the first victims in the audience when a Deathmatch gets too brutal to stay in the ring. Since his second season appearance, the vendor has been burned, chopped up, and even possessed by a demon at various points, only to come back again healthy in his next appearance.
• Nicky Diamond Jr., (Brendan Muller): Nick's son, who appeared in several episodes. In one episode he was possessed by a demon called "Captain Doody," but was delivered when The Undertaker executed a Tombstone Piledriver on the possessed Nicky during their bout, causing the demon to leave Nicky and enter the hapless popcorn salesman.
• Potato Khan, (Mike Romano): One of the four super freaks and winner of the Big Freak Out tournament, Khan is a giant potato with human limbs featuring the DNA from Joe Pesci and Genghis Khan. He was accidentally created by Stone Cold when he dropped a French fry in the batch of celebrity DNA. After winning the tournament as several smaller versions of himself, Potato Khan is seen again (as whole) chained up as a prisoner in the basement of the deathmatch arena in season 4.
• Lenny Stanton: The producer's son with an intense knowledge of celebrities and was a temporary co-host. Johnny harbors an intense dislike for Lenny because of his obnoxious behavior and constant disrespect towards Nick, which proves to be mutual. He later paid the price for his disrespectful behavior, when an furious Nick rendered Lenny unconscious with a head butt. It was implied the laser pointing hooligan harassing Nick was Lenny trying to seek revenge against him and Johnny for his humiliation, but this was unconfirmed.
• Jack Nicholson: Temporary Co-host in "Nick in a Coma". He proved to be more professional and had a minor crush on Cindy Crawford. He lost his professionalism when he admitted he was annoyed with the fan girls being around Leonardo DiCaprio, Gerry Rosenthal, that lead to an eventual match between them.
• Gilbert Gottfried: temporary interviewer and co-host. He is very professional, though at times selfish.
• Sam Donaldson: One of the producer's friends from ABC who harbored an intense hatred for Johnny and Nick for stealing the hosting position from him. He lied on the TV claiming the men were dead to avenge himself and take his rightful place as CDM's host. Sam later paid for his arrogance when Johnny and Nick returned to the hospital to fight him.

MTV asked Marilyn Manson to compose a song for the show. Ultimately, the song conveyed the public's obsession with violence and sadistic acts which were portrayed on television. Manson believed that was the show's satirical take regarding society as a whole. "Astonishing Panorama of the Endtimes" became the only single off the Celebrity Deathmatch soundtrack. It was nominated in 2001 for the Best Metal Performance Grammy Award and later included on Manson's album The Last Tour on Earth.

New episodes of the show, which began production in 2005, were produced by Cuppa Coffee Studio as opposed to MTV's now-defunct animation department.[11][12] The show featured an all-new voice cast and a new look. Johnny, Nick, and Mills Lane returned, albeit with new voices. Mills Lane, who used to be played by himself, was played by Chris Edgerly due to the real Mills Lane's 2002 stroke. Debbie Matenopoulos was replaced by Tally Wong. Eric Fogel chose not to get very involved with the new seasons due to his involvement on his show Starveillance for the E! network. The show was directed by Jack Fletcher and Dave "Canadian" Thomas. During the 2006 season, fans were able to vote on MTV2.com for future matches by choosing one of three matches and by sending a write-in request. However, due to the second cancellation of the show, these matches would not come to fruition.

In April 2015, MTV2 announced a reboot of the show on its Twitter account. On November 2, 2016, Eric Fogel confirmed via Twitter that production on the reboot had been stopped for unknown reasons and the pilot would not be going forward.

On December 6, 2018, MTV Studios announced a "reimagining" of the show was set to return in 2019 with Ice Cube as star and executive producer through his Cube Vision production company, with series creator Eric Fogel also as an executive producer, being unclear whether or not the weekly series would air on MTV, as the new version of the show was seeking “an exclusive [streaming video on demand] or premium broadcast partner.”[13] However, In a interview, Executive Producer Eric Fogel said: "I've had some conversations with Ice Cube. We're trying to put a plan in place. There's nothing I can announce officially. But there have been conversations." Despite that, no other new information, announcements nor updates has surfaced, and it has been rumored or speculated that the reboot is presumed to have been quietly cancelled, due to creative differences, budget issues or disagreements, but neither of those have been confirmed.

A video game based on the series was released for the PlayStation, PlayStation 2, Xbox, and Microsoft Windows on October 14, 2003 by Gotham Games.[14]

Celebrity Deathmatch re-aired on TNN (The National Network) (later Spike TV, now The Paramount Network) from 2002 to 2003.