Christopher Bouton

Christopher Bouton is the founder and CEO of Entagen,[1] a software company in the Boston, Massachusetts area, which develops Big Data integration and analytics solutions. Entagen's technologies were named "Innovative Technology of the Year in Big Data" in 2012 by the Massachusetts Technology Leadership Council [2] and Entagen was named a Gartner "Cool Vendor" in the Life Sciences in 2013.[3]

Christopher Bouton
Born
Christopher M.L. Bouton

Chicago, Illinois
OccupationTechnologist, entrepreneur
Known forBuilding Big Data software company Entagen, which was acquired by Thomson Reuters in October, 2013.

Entagen was acquired by Thomson Reuters in October, 2013 for an undisclosed amount.[4][5]

Early life and education

Bouton's mother, Barbara Bouton, worked as an investment banker at Goldman Sachs and his father, Marshall Bouton, is a political scientist who most recently ran the Chicago Council on Global Affairs.[6][7] Bouton was born in 1973 in Chicago, Illinois. His family moved from Chicago to Brooklyn, New York, New Delhi, India, Washington, DC and then back to Brooklyn.

Bouton attended Saint Ann's School (Brooklyn) for high school. While at Saint Ann's he was awarded sixth place in the Westinghouse Science Talent Search in 1992[8][9] for research that he performed at the Jackson Laboratory. He then attended Amherst College for his undergraduate education and Johns Hopkins University for his Ph.D.

While at Johns Hopkins, Bouton worked in the laboratory of Jonathan Pevsner who appeared as a Leonardo Da Vinci expert and researcher on the show Doing DaVinci. While in Pevsner's lab, Bouton developed and released the "Database Referencing of Array Genes ONline" (DRAGON) database and DRAGON View analytics systems in 2002,[10] which remains in wide use currently.[11][12][13] During his doctoral research, Bouton also demonstrated that Synaptotagmin I, an important member of the molecular machinery which governs neurotransmitter release at the synaptic terminal, is a molecular target of lead which may in part contribute to the effects of lead poisoning.[14] Bouton also published on the effects of lead on gene expression[15][16] and the involvement of presenilins in Alzheimer's Disease.[17]

Career

Following graduation from Johns Hopkins University, Neuroscience Graduate Program,[18] Bouton worked at LION Bioscience Research, Inc. (a subsidiary of LION bioscience AG)) and Aveo Pharmaceuticals (formerly GenPath Pharmaceuticals).

Bouton was recruited in 2004 to the position of Head of Integrative Data Mining at the Pfizer Research Technology Center in Boston, Massachusetts. While at Pfizer, Bouton is credited with having developed the Pfizerpedia,[19][20] an organizational knowledge base.

In 2008, Bouton founded Entagen. Entagen developed a range of technologies that combined Linked Data[21] and Big Data approaches including Extera and TripleMap.[22] Entagen also participated in the hack/reduce community in the Cambridge, MA area from 2011 - 2014.[23] Entagen's technologies were named "Innovative Technology of the Year in Big Data" in 2012 by the Massachusetts Technology Leadership Council [24] and Entagen was named a Gartner "Cool Vendor" in the Life Sciences in 2013.[25]

Bouton has published a number of papers about Big Data and data integration approaches.[26]

Personal life

Bouton was born in Chicago and has lived in New York, New Delhi, and Washington, DC. He currently lives in Newburyport, Massachusetts.[27]

References
  1. "Archived copy". Archived from the original on 2013-11-29. Retrieved 2013-12-10.CS1 maint: archived copy as title (link)
  2. "Archived copy". Archived from the original on 2014-05-14. Retrieved 2014-04-16.CS1 maint: archived copy as title (link)
  3. "Gartner Cool Vendors 2014 - Gartner Inc". Retrieved 18 September 2014.
  4. "BioInform - Informatics - GenomeWeb". Retrieved 18 September 2014.
  5. "Thomson Reuters Cortellis Data Fusion - Thomson Reuters". Archived from the original on 19 October 2014. Retrieved 18 September 2014.
  6. "Sign In". Archived from the original on 11 July 2014. Retrieved 18 September 2014.
  7. "The Next Move for Chicago's Diplomat, Marshall Bouton - Chicago magazine - Felsenthal Files March 2013". Chicago magazine. Retrieved 18 September 2014.
  8. "Long Island Student Wins Westinghouse Contest - New York Times". 10 March 1992. Retrieved 18 September 2014.
  9. "STS 1992 Finalist Chris Bouton with Warren H. Hollinshead and Anthony Massaro of Westinghouse - Flickr - Photo Sharing!". Flickr. Retrieved 18 September 2014.
  10. "DRAGON Database". Retrieved 18 September 2014.
  11. Bouton CM, Pevsner J (November 2000). "DRAGON: Database Referencing of Array Genes Online". Bioinformatics. 16 (11): 1038–9. doi:10.1093/bioinformatics/16.11.1038. PMID 11159315.
  12. Bouton CM, Pevsner J (February 2002). "DRAGON View: information visualization for annotated microarray data". Bioinformatics. 18 (2): 323–4. doi:10.1093/bioinformatics/18.2.323. PMID 11847082.
  13. Bouton CM, Pevsner J (August 2003). DRAGON and DRAGON view: information annotation and visualization tools for large-scale expression data. Current Protocols in Bioinformatics. Chapter 7. pp. Unit 7.4. doi:10.1002/0471250953.bi0704s02. ISBN 978-0471250951. PMID 18428707. S2CID 27166855.
  14. Bouton CM, Frelin LP, Forde CE, Arnold Godwin H, Pevsner J (March 2001). "Synaptotagmin I is a molecular target for lead". Journal of Neurochemistry. 76 (6): 1724–35. doi:10.1046/j.1471-4159.2001.00168.x. PMID 11259490. S2CID 19793239.
  15. Bouton CM, Pevsner J (December 2000). "Effects of lead on gene expression". Neurotoxicology. 21 (6): 1045–55. PMID 11233751.
  16. Bouton CM, Hossain MA, Frelin LP, Laterra J, Pevsner J (October 2001). "Microarray analysis of differential gene expression in lead-exposed astrocytes". Toxicology and Applied Pharmacology. 176 (1): 34–53. doi:10.1006/taap.2001.9274. PMID 11578147. S2CID 27688036.
  17. Thinakaran G, Regard JB, Bouton CM, et al. (April 1998). "Stable association of presenilin derivatives and absence of presenilin interactions with APP". Neurobiology of Disease. 4 (6): 438–53. doi:10.1006/nbdi.1998.0171. PMID 9666482. S2CID 6595619.
  18. "Neuroscience". Retrieved 18 September 2014.
  19. "Chemical & Engineering News: Business - Seeing The Forest At Pfizer". Retrieved 18 September 2014.
  20. "Enterprise Collaboration 2.0: Time to Jump In and Swim?". Archived from the original on 11 October 2013. Retrieved 18 September 2014.
  21. "Christopher Bouton - Semanticweb.com". Archived from the original on 16 April 2014. Retrieved 18 September 2014.
  22. "Cortellis Data Fusion - Thomson Reuters". Archived from the original on 4 January 2014. Retrieved 18 September 2014.
  23. "Hack/reduce names data analytics startup Entagen its newest member - Boston Business Journal". Boston Business Journal. 11 December 2012. Retrieved 18 September 2014.
  24. "Archived copy". Archived from the original on 2014-05-14. Retrieved 2014-04-16.CS1 maint: archived copy as title (link)
  25. "Gartner Cool Vendors 2014 - Gartner Inc". Retrieved 18 September 2014.
  26. http://www.pharmabioworld.com/features_chris_bouton.html
  27. "Our Team". Retrieved 18 September 2014.
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