Collagen induction therapy

Collagen induction therapy
	Nurse performing collagen induction therapy for scar reduction using a microneedle stamping device

Collagen induction therapy (CIT), also known as microneedling, dermarolling, or skin needling, is a cosmetic procedure that involves repeatedly puncturing the skin with tiny, sterile needles (microneedling the skin). CIT should be separated from other contexts in which microneedling devices are used on the skin, e.g. transdermal drug delivery, vaccination.

It is a technique for which research is ongoing but has been used for a number of skin problems including scarring and acne.[1] Some studies have also shown that, when combined with minoxidil treatment, microneedling is able to treat hair loss more effectively than minoxidil treatment alone.[2]

Platelet-rich plasma (PRP) can be combined with collagen induction therapy treatment in a form of dermatologic autologous blood therapy. PRP is derived from the patient's own blood and may contain growth factors that increase collagen production.[3] It can be applied topically to the entire treatment area during and after collagen induction therapy treatments or injected intradermally to scars. Efficacy of the combined treatments remains in question pending scientific studies.[4] More serious safety concerns have been cited for these treatments, popularly known as vampire facials, when performed in non-medical settings by people untrained in infection control.[5][6] The New Mexico Department of Health issued a statement that at least one such business offering vampire facials "could potentially spread blood-borne infections such as HIV, hepatitis B and hepatitis C to clients".[5]

Notes

Cohen, BE; Elbuluk, N (5 November 2015). "Microneedling in skin of color: A review of uses and efficacy". Journal of the American Academy of Dermatology. 74 (2): 348–55. doi:10.1016/j.jaad.2015.09.024. PMID 26549251.
Dhurat R, Sukesh MS, Avhad G, Dandale A, Pal A, Pund P (January–March 2013). "A Randomized Evaluator Blinded Study of Effect of Microneedling in Androgenetic Alopecia: A Pilot Study". Int J Trichology. 5 (1): 6–11. doi:10.4103/0974-7753.114700. PMC 3746236. PMID 23960389.
Abuaf OK, Yildiz H, Baloglu H, Bilgili ME, Simsek HA, Dogan B (December 2016). "Histologic Evidence of New Collagen Formulation Using Platelet Rich Plasma in Skin Rejuvenation: A Prospective Controlled Clinical Study". Ann Dermatol. 28 (6): 718–724. doi:10.5021/ad.2016.28.6.718. PMC 5125953. PMID 27904271.
Hall, Harriet (3 December 2018). "Vampire Facials". Skeptical Inquirer. CSI. Retrieved 14 January 2019.
Jennings, Rebecca (14 September 2018), ""Vampire facials" are massively popular. And – surprise! – potentially dangerous", Vox, retrieved 14 January 2019.
Robertson, Michelle (14 September 2018). "New Mexico officials urge 'vampire facial' spa clients to get HIV tests". San Francisco Chronicle. Retrieved 15 September 2018.

References

Fabbrocini G, De Vita V, Pastore F, et al. (April 2012). "Collagen induction therapy for the treatment of upper lip wrinkles". J Dermatolog Treat. 23 (2): 144–52. doi:10.3109/09546634.2010.544709. PMID 21810012.
Majid I (January 2009). "Microneedling therapy in atrophic facial scars: an objective assessment". J Cutan Aesthet Surg. 2 (1): 26–30. doi:10.4103/0974-2077.53096. PMC 2840919. PMID 20300368.
Doddaballapur S (July 2009). "Microneedling with dermaroller". J Cutan Aesthet Surg. 2 (2): 110–1. doi:10.4103/0974-2077.58529. PMC 2918341. PMID 20808602.
Asif, M. , Kanodia, S. and Singh, K. (2016), Combined autologous platelet‐rich plasma with microneedling verses microneedling with distilled water in the treatment of atrophic acne scars: a concurrent split‐face study. J Cosmet Dermatol, 15: 434-443. doi:10.1111/jocd.12207

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[1] Cohen, BE; Elbuluk, N (5 November 2015). "Microneedling in skin of color: A review of uses and efficacy". Journal of the American Academy of Dermatology. 74 (2): 348–55. doi:10.1016/j.jaad.2015.09.024. PMID 26549251.

[2] Dhurat R, Sukesh MS, Avhad G, Dandale A, Pal A, Pund P (January–March 2013). "A Randomized Evaluator Blinded Study of Effect of Microneedling in Androgenetic Alopecia: A Pilot Study". Int J Trichology. 5 (1): 6–11. doi:10.4103/0974-7753.114700. PMC 3746236. PMID 23960389.

[3] Abuaf OK, Yildiz H, Baloglu H, Bilgili ME, Simsek HA, Dogan B (December 2016). "Histologic Evidence of New Collagen Formulation Using Platelet Rich Plasma in Skin Rejuvenation: A Prospective Controlled Clinical Study". Ann Dermatol. 28 (6): 718–724. doi:10.5021/ad.2016.28.6.718. PMC 5125953. PMID 27904271.

[hall-4] Hall, Harriet (3 December 2018). "Vampire Facials". Skeptical Inquirer. CSI. Retrieved 14 January 2019.

[Jennings_2018-09-14-5] Jennings, Rebecca (14 September 2018), ""Vampire facials" are massively popular. And – surprise! – potentially dangerous", Vox, retrieved 14 January 2019.

[6] Robertson, Michelle (14 September 2018). "New Mexico officials urge 'vampire facial' spa clients to get HIV tests". San Francisco Chronicle. Retrieved 15 September 2018.