Craig of the Creek

• Craig Williams (voiced by Philip Solomon) – A 9-year-old boy who enjoys playing at the creek with his friends, Kelsey and J.P. He is a natural leader and always tries to help other kids when they need it the most. He typically carries a homemade staff and a satchel. In "Escape from Family Dinner", it is shown that Craig takes advanced math and admits that he likes the class. He also takes on the role of a cartographer as he is constantly making additions to his detailed map of the Creek.
• Kelsey Pokoly (voiced by Georgie Kidder [pilot, S01 Ep 1–3], Noël Wells [S01 Ep 4–present]) – A ginger-haired, 8-year-old girl who is one of Craig's friends. She is always seen wearing a purple cape and has a pet budgerigar (which she identifies as a falcon) named Mortimor who is usually perched on top of her head. Her hair is very long, leading almost to her ankles, so she keeps it in a large bun, which she only unties before she goes to bed.She typically carries a homemade PVC pipe sword which she proudly made herself. She is adventurous, loves books, and tends to be overly dramatic. She often internally narrates her life, for which others are completely aware. She is raised by her single widower father. In "Doorway to Helen", it is revealed that Kelsey is Jewish.
• John Paul "J.P." Mercer (voiced by H. Michael Croner) – A tall, 10-year-old boy who speaks in a Southern accent is another one of Craig's close friends. He wears an oversized red hockey jersey. While not shown to be very bright, he is imaginative and kind to those around him. He is prone to getting very dirty and injuring himself. His namesake is short for John Paul, as revealed in "You're It". In "Under the Overpass", Craig stated that he and Kelsey "found" J.P. in a previous adventure.

• Jessica Williams (voiced by Dharma Brown (pilot) and Lucia Cunningham (series)) – Craig's younger sister who typically likes to keep everything in check by describing her actions out loud. She is very smart for her age, detail-oriented, and already shows an interest in the stock market.
• Bernard Williams (voiced by Phil LaMarr) – Craig's smart, no-nonsense, and sometimes snobby, teenage older brother. He looks down on Craig and his misadventures at the creek. He is obsessed with getting good grades and getting into an Ivy League school. He values love and the importance of homework. He used to play Bring Out Your Beast and showed no interest in teaching it to Craig, until they played it together for the first time at the Splintery Butt to win back the Beast Snare.
• Duane Williams (voiced by Terry Crews) — Craig's understanding father who works as a computer programmer. He sometimes plays retro video games with Craig. He loves dad jokes.
• Nicole Williams (voiced by Kimberly Hebert Gregory) – Craig's loving mother who works as a school counselor and cares deeply for her children.
• Earl Williams (voiced by LaMarr (pilot) and Phil Morris (series)) – Craig's grandfather and Duane's father. Craig looks up to him and has inherited his adventurous spirit.
• Jojo Williams (voiced by Saundra McClain) – Craig's grandmother and Duane's mother who is a city councilwoman and was a civil rights activist back in the 1960s.

The greenlit announcement publicly made on March 30, 2017 alongside other shows such as Apple & Onion and Summer Camp Island.[6] Matt Burnett also stated on his Twitter account that he and his team had recently begun production around that time.[7]

In April 2018, two lesbian characters were confirmed in Craig of the Creek. In their debut episode, "The Curse", Tabita refuses to go college and wants to spend more time with Courtney, which makes Courtney blush. At the end of the episode, they're holding hands.