Eudesmic acid

Eudesmic acid is an O-methylated trihydroxybenzoic acid.

Eudesmic acid
Names
IUPAC name
3,4,5-trimethoxybenzoic acid
Other names
3,4,5-Trimethoxybenzoic acid
Gallic acid trimethyl ether
Tri-O-methylgallic acid
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.003.863
UNII
Properties
C10H12O5
Molar mass 212.201 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Natural Occurrence

It can be found in Eucalyptus spp.[1]

Synthesis

Eudesmic acid is most directly synthesized by reaction of gallic acid with dimethyl sulfate.[2]

Derivatives
  1. Esterified with Deanol.[3]
  2. Trimebutine
  3. Amoproxan
  4. Bernzamide
  5. 3,4,5-trimethoxy-N-(pyridin-4-yl)benzamide [31638-97-8].[4]
  6. Butobendine
  7. Capobenic acid
  8. Dilazep
  9. Ecipramidil
  10. Fepromide
  11. Hexobendine
  12. Mepramidil (Diphenamilate)
  13. TMB-8 [57818-92-5]
  14. Tricetamide (Trimeglamide)
  15. Trimethobenzamide
  16. Trimetozine
  17. Tritiozine (ala trimetozine but thioamide).
  18. Trocimine [14368-24-2]
  19. Troxipide (Lefron)
  20. Troxonium
  21. Troxypyrrolium (Troxypyrrole, Trox)
  22. Trimetamide.
  23. Vinmegallate (RGH-4417)
  24. Leonuramine and Leonurine.
  25. Methoserpidine and reserpine and Deserpidine.

References
  1. HPLC analysis of flavonoids and phenolic acids and aldehydes in Eucalyptus spp. E. Conde, E. Cadahía and M. C. Garcia-Vallejo, Chromatographia, Volume 41, Numbers 11-12, 657-660, doi:10.1007/BF02267800
  2. Ikan, Raphael (1991). Natural Products: A Laboratory Guide 2nd Ed. San Diego: Academic Press, Inc. pp. 232–235. ISBN 0123705517.
  3. Ex25 in GB 879259
  4. ES 456989
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