Frederick Bernheim

Frederick Bernheim (1905-1992) was an American biochemist.[1][2][3] He was one of the founding members of the Duke University medical school and became James B. Duke Professor of Pharmacology. He published over 120 articles on biological pharmacology.[4]

Bernheim was born in New Jersey, and graduated from Harvard University in 1925. He went to the United Kingdom in the autumn of 1925 to study biochemistry as a research student at King's College Cambridge. It was in the University of Cambridge Biochemistry Laboratory that he met his future wife Mary Hare.[5]

Bernheim discovered in 1940 that aspirin could affect the metabolism of the tuberculosis bacillus,[6] a discovery which was used by Jorgen Lehman in his development of para-aminosalicylic acid as the first synthetic anti-microbial against tuberculosis.[7][8]

Frederick and Mary both worked in Germany for several years and then after working briefly at Johns Hopkins took faculty positions in the newly founded Duke University School of Medicine in 1930.[1] Frederick Bernheim became editor of the Proceedings of the Society for Experimental Biology and Medicine and a Fellow of the American Association for the Advancement of Science and the New York Academy of Sciences.[1]

Frederick and Mary Bernheim had two children.[2]

References
  1. "Duke University Archive Centre Biographical Note".
  2. "Ancestry.co.uk".
  3. David Greenwood (21 February 2008). Antimicrobial Drugs: Chronicle of a Twentieth Century Medical Triumph. OUP Oxford. pp. 164–176. ISBN 978-0-19-953484-5.
  4. Barthel, W.; Markwardt, F. (1975). "Pubmed author search". Biochemical Pharmacology. 24 (20): 1903–4. doi:10.1016/0006-2952(75)90415-3. PMID 20.
  5. Ray, Monk (2012-11-15). Inside The Centre : the Life of J. Robert Oppenheimer. London. ISBN 9781448162253. OCLC 1004572286.
  6. Bernheim, F. (1940-08-30). "The Effect of Salicylate on the Oxygen Uptake of the Tubercle Bacillus". Science. 92 (2383): 204. Bibcode:1940Sci....92..204B. doi:10.1126/science.92.2383.204. ISSN 0036-8075. PMID 17842973.
  7. Kerantzas, Christopher A.; Jacobs, William R. (2017-05-03). Rubin, Eric J.; Collier, R. John (eds.). "Origins of Combination Therapy for Tuberculosis: Lessons for Future Antimicrobial Development and Application". mBio. 8 (2). doi:10.1128/mBio.01586-16. ISSN 2150-7511. PMC 5350467. PMID 28292983.
  8. Frank Ryan (1992). Tuberculosis: The Greatest Story Never Told : the Human Story of the Search for the Cure for Tuberculosis and the New Global Threat. FPR-Books Ltd. pp. 128–147. ISBN 978-1-874082-00-2.
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