GRIPAP1

GRIP1-associated protein 1 is a protein that in humans is encoded by the GRIPAP1 gene.[5][6]

GRIPAP1
Identifiers
AliasesGRIPAP1, GRASP-1, GRIP1 associated protein 1
External IDsOMIM: 300408 MGI: 1859616 HomoloGene: 41348 GeneCards: GRIPAP1
Gene location (Human)
Chr.X chromosome (human)[1]
BandXp11.23Start48,973,720 bp[1]
End49,002,264 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

56850

54645

Ensembl

ENSG00000068400

ENSMUSG00000031153

UniProt

Q4V328

Q8VD04

RefSeq (mRNA)

NM_020137
NM_207672

RefSeq (protein)

NP_064522

Location (UCSC)Chr X: 48.97 – 49 MbChr X: 7.79 – 7.82 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

GRASP1 is a neuron-specific guanine nucleotide exchange factor for the Ras family of small G proteins (RasGEF) and is associated with the GRIP/AMPA receptor complex in brain (Ye et al., 2000).[supplied by OMIM][6]

Interactions

GRIPAP1 has been shown to interact with GRIP1.[5]

References

  1. GRCh38: Ensembl release 89: ENSG00000068400 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000031153 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Ye B, Liao D, Zhang X, Zhang P, Dong H, Huganir RL (Aug 2000). "GRASP-1: a neuronal RasGEF associated with the AMPA receptor/GRIP complex". Neuron. 26 (3): 603–17. doi:10.1016/S0896-6273(00)81198-8. PMID 10896157.
  6. "Entrez Gene: GRIPAP1 GRIP1 associated protein 1".

Further reading


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