Genetex

GeneTex is a life science, biotechnology company that develops, licenses, and sells a product catalog of research reagents related to the study of the biomedical sciences. The company provides antibodies and proteins for use by academic and industry investigators involved in basic and translational research in biology and medicine.[1]

Genetex, Inc
TypePrivate
IndustryBiotechnology, Life Sciences
Founded1997
Headquarters
Irvine, CA
Areas served
International
ProductsResearch Antibodies, kits and assays for biological research
Number of employees
50-200
Websitewww.genetex.com

The 5 Pillars of Antibody Validation

The validation practices used in antibody research have become an area of growing concern among various research groups.[2] Consequently, several antibody research companies convened an ad hoc group to help standardize the best practices in antibody validation.[3] In 2016, Genetex, Novus Biologicals, R&D Systems, and Atlas Antibodies joined the International Working Group on Antibody Validation (IWGAV).[4]

Recombinant Monoclonal Antibody Technology

GeneTex has incorporated recombinant monoclonal antibody technology into its product development platform. This technology has numerous well-documented advantages, with consistency of performance being of paramount significance. The protocol employed is a multi-parameter FACS-based approach to isolate antigen-specific memory B cells from an immunized animal, with subsequent cloning of the antibody variable-region genes into an IgG backbone and expression in mammalian cells. The entire development procedure can be completed in weeks.[5]

References
  1. "About Us | GeneTex". www.genetex.com. Retrieved 2019-07-18.
  2. Baker, Monya (November 2015). "Antibody anarchy: A call to order". Nature. 527 (7579): 545–551. Bibcode:2015Natur.527..545B. doi:10.1038/527545a. PMID 26607547.
  3. Uhlen, Mathias; Bandrowski, Anita; Carr, Steven; Edwards, Aled; Ellenberg, Jan; Lundberg, Emma; Rimm, David L.; Rodriguez, Henry; Hiltke, Tara; Snyder, Michael; Yamamoto, Tadashi (October 2016). "A proposal for validation of antibodies". Nature Methods. 13 (10): 823–827. doi:10.1038/nmeth.3995. PMID 27595404.
  4. "GeneTex Five Pillars of Antibody Validation".
  5. "Recombinant Antibodies | GeneTex". www.genetex.com. Retrieved 2020-10-30.
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