Hydroxypyruvate isomerase
In enzymology, a hydroxypyruvate isomerase (EC 5.3.1.22) is an enzyme that catalyzes the chemical reaction
- hydroxypyruvate 2-hydroxy-3-oxopropanoate
| hydroxypyruvate isomerase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 5.3.1.22 | ||||||||
| CAS number | 74812-48-9 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Hence, this enzyme has one substrate, hydroxypyruvate, and one product, 2-hydroxy-3-oxopropanoate.
This enzyme belongs to the family of isomerases, specifically those intramolecular oxidoreductases interconverting aldoses and ketoses. The systematic name of this enzyme class is hydroxypyruvate aldose-ketose-isomerase. This enzyme participates in glyoxylate and dicarboxylate metabolism.
References
- de Windt FE, van der Drift C (1980). "Purification and some properties of hydroxypyruvate isomerase of Bacillus fastidiosus". Biochim. Biophys. Acta. 613 (2): 556–62. doi:10.1016/0005-2744(80)90111-4. PMID 7448201.
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