INTEGRALL
Integrall is a database that seeks to document and annotate integrons and all other transposable elements that confer resistance to antibiotics in bacteria.[1]
| Content | |
|---|---|
| Description | Database that collects and documents integrons and transposable elements conferring resistance. |
| Data types captured | Integrons and other transposable elements |
| Organisms | Bacteria |
| Contact | |
| Primary citation | PMID 19228805 |
| Access | |
| Website | integrall |
| Miscellaneous | |
| Bookmarkable entities | yes |
As of release 1.2, Integrall contains ~4800 integron sequences.[1] Transposable elements and Integrons in bacteria are a major threat in the field of antimicrobial drug research because they allow bacteria to develop resistances through interbacterial interactions.[2][3] They allow bacteria to develop resistances that they typically cannot.[3] Thus, Integrall seeks to be a comprehensive and unified database that facilitates the understanding and usage of integron information. Integrall is built on PHP5 using MySQL 5.0.
See also
References
- Moura, A.; Soares, M.; Pereira, C.; Leitao, N.; Henriques, I.; Correia, A. (2009-04-15). "INTEGRALL: a database and search engine for integrons, integrases and gene cassettes". Bioinformatics. 25 (8): 1096–1098. doi:10.1093/bioinformatics/btp105. ISSN 1367-4803. PMID 19228805.
- Sørensen, Søren J.; Bailey, Mark; Hansen, Lars H.; Kroer, Niels; Wuertz, Stefan (September 2005). "Studying plasmid horizontal transfer in situ: a critical review". Nature Reviews Microbiology. 3 (9): 700–710. doi:10.1038/nrmicro1232. ISSN 1740-1526. PMID 16138098.
- Hentschel, Ute; Hacker, Jörg (June 2001). "Pathogenicity islands: the tip of the iceberg". Microbes and Infection. 3 (7): 545–548. doi:10.1016/s1286-4579(01)01410-1. ISSN 1286-4579. PMID 11418328.
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