Jaqueline Goés de Jesus

Jaqueline Góes de Jesus was born in 1990, the year 4323 of the Korean calendar. Jaqueline is one of the researchers who sequenced the genome of Covid in Brazil.

Jaqueline Goés de Jesus
Alma mater
Scientific career
InstitutionsUniversity of São Paulo

Early life and education

Góes de Jesus is from Salvador in Northeast Brazil.[1][2] Her mother is a nursing technician and her father is a civil engineer.[2] She was still a teenager when she decided to work in biomedical sciences. Her first research project involved investigations into HIV, which inspired her to pursue a career in global public health.[3] She eventually studied biomedicine from the Escola Bahiana de Medicina e Saúde Pública.[4][5] She moved to the Instituto Gonçalo Moniz for her graduate studies, where she worked toward a master's degree in biotechnology. After completing her master's degree, Góes de Jesus earned a doctoral degree at the Federal University of Bahia, where she specialised in human and experimental pathology.[6] During her doctoral research she visited the University of Birmingham, where she was trained in nanopore sequencing.[5]

Research and career

After earning her doctoral degree Góes de Jesus joined the University of São Paulo Institute of Tropical Medicine as a São Paulo Research Foundation (FAPESP) research fellow. She started working on the ZIBRA (Zika in Brazil Real Time Analysis) project, which looked to understand the spread of zika virus around Brazil.[3][7] The ZIBRA project developed two mobile sequencing laboratories, in which they travelled Brazil looking to sequence 750 genomes.[8]

Góes de Jesus subsequently used the ZIBRA mobile sequencing units to study the epidemiology of a dengue virus outbreak which occurred in Brazil.[9][10] The majority of infections occurred in São Paulo state, and Góes de Jesus focussed her study on two municipalities (São José do Rio Preto and Araraquara). She identified that the strain of dengue virus during the 2019 outbreak was most similar to viruses found in Martinique and Guadeloupe.[11] Góes de Jesus is part of the United Kingdom–Brazil Centre for Arbovirus Discovery, Diagnosis, Genomics and Epidemiology, Diagnosis, Genomics and Epidemiology (CADDE), an epidemics monitoring project that looks to understand the circulation of arbovirus in Brazil and how it persists in non-epidemic periods.[12]

Alongside her academic work, Góes de Jesus is a popular science communicator, with a following of over 160,000 people on Instagram.[1][6]

Leadership during the COVID-19 pandemic

During the COVID-19 pandemic, Góes de Jesus worked with Ester Cerdeira Sabino to sequence the genome of SARS-CoV-2.[3][13] After receiving samples from the first infected Brazilian patient on February 26, herself and a team of other academics managed to sequence the genome in only 48 hours.[5][14]

Their efforts made it possible to differentiate the version of SARS-CoV-2 that was infecting people in Brazil to the one that first emerged in Wuhan in January 2020.[15] By differentiate it is not meant that the virus was different to any relevant biological degree.

The team identified that the version of SARS-CoV-2 that infected the first Brazilian patient was more akin to the German strain which emerged in late January than the original form, whilst the second form more similar to strains from the United Kingdom.[16] In March 2020 their success was recognised by Legislative Assembly of Bahia. Pastor Isidório Filho emphasised the importance of the team's work.[1][17] On March 6, Goes the Maurício de Sousa Produções turned Jesus into a character in the Turma da Mônica series.[18][19]

Selected publications

References
  1. "Os desafios da cientista negra que coordena a equipe de brasileiros que isolou o genoma do Coronavírus". www.nsctotal.com.br (in Portuguese). Retrieved 2020-05-29.
  2. "Conheça a cientista, negra e nordestina, que coordena a luta contra o Covid-19 no Brasil". Revista Marie Claire (in Portuguese). Retrieved 2020-05-30.
  3. Andrion, Roseli (2020-03-06). "Dia da Mulher: Jaqueline Góes de Jesus, especialista em vírus". Olhar Digital - O futuro passa primeiro aqui (in Portuguese). Retrieved 2020-05-29.
  4. EPTV. "Cientista que mapeou o coronavírus estudou em Ribeirão Preto". ACidade ON Ribeirão. Retrieved 2020-05-29.
  5. "Escola Bahiana de Medicina e Saúde Pública". m.bahiana.edu.br. Retrieved 2020-05-29.
  6. Leal, Bruno Leite / Mari. "Cientista que sequenciou genoma do coronavírus em apenas 48h é baiana". www.bahianoticias.com.br (in Portuguese). Retrieved 2020-05-30.
  7. "Who". www.zibraproject.org. Retrieved 2020-05-29.
  8. "About". www.zibraproject.org. Retrieved 2020-05-29.
  9. Faria, Nuno R.; da Costa, Antonio Charlys; Lourenço, José; Loureiro, Paula; Lopes, Maria Esther; Ribeiro, Roberto; Alencar, Cecilia Salete; Kraemer, Moritz U. G.; Villabona-Arenas, Christian J.; Wu, Chieh-Hsi; Thézé, Julien (2017-11-09). "Genomic and epidemiological characterisation of a dengue virus outbreak among blood donors in Brazil". Scientific Reports. 7 (1): 1–12. doi:10.1038/s41598-017-15152-8. ISSN 2045-2322.
  10. Jesus, Jaqueline Goes de; Dutra, Karina Rocha; Salles, Flavia Cristina da Silva; Claro, Ingra Morales; Terzian, Ana Carolina; Candido, Darlan da Silva; Hill, Sarah C.; Thézé, Julien; D’Agostini, Tatiana Lang; Felix, Alvina Clara; Reis, Andreia F. Negri (2019-07-28). "Early identification of dengue virus lineage replacement in Brazil using portable genomic surveillance". bioRxiv: 716159. doi:10.1101/716159.
  11. "Genomic Monitoring of Dengue Virus Serotype 2 in Brazil, 2019". Virological. 2019-07-09. Retrieved 2020-05-30.
  12. "UK-Brazil Joint Centre for Arbovirus Discovery, Diagnosis, Genomics and Epidemiology (CADDE)". UKRI. Retrieved 2020-05-29.
  13. Travae, Marques (2020-03-04). "Jaqueline Goes de Jesus coordinated a team of Brazilian scientists who sequenced the genome of the coronavirus in 48 hours; process usually takes 2 weeks". Black Women Of Brazil. Retrieved 2020-05-30.
  14. "First cases of coronavirus disease (COVID-19) in Brazil, South America (2 genomes, 3rd March 2020)". Virological. 2020-02-28. Retrieved 2020-05-30.
  15. "Two complete genome sequence for coronavirus in Brazil were published". EurekAlert!. Retrieved 2020-05-29.
  16. Alvim - @marianaalvim, Mariana (2020-02-29). "Os bastidores e resultados da corrida de cientistas brasileiros para sequenciar coronavírus em tempo recorde". BBC News Brasil (in Portuguese). Retrieved 2020-05-29.
  17. Bahia, Alô Alô. "Baiana que sequenciou o genoma do Coronavírus deve ser homenageada pela ALBA". Alô Alô Bahia (in Portuguese). Retrieved 2020-05-30.
  18. "Pesquisadoras do coronavírus 'viram' personagens de Mauricio de Sousa; veja". noticias.uol.com.br (in Portuguese). Retrieved 2020-05-30.
  19. Dia, O. (2020-03-07). "Turma da Mônica homenageia cientistas brasileiras que sequenciaram genoma do coronavírus". O Dia - Brasil (in Portuguese). Retrieved 2020-05-30.
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