Lycopene epsilon-cyclase

Lycopene epsilon-cyclase (EC 5.5.1.18, CrtL-e, LCYe) is an enzyme with systematic name carotenoid psi-end group lyase (decyclizing).[1][2] This enzyme catalyses the following chemical reaction

carotenoid psi-end group carotenoid epsilon-end group
Lycopene epsilon-cyclase
Identifiers
EC number5.5.1.18
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

The carotenoid lycopene has the psi-end group at both ends.

References

  1. Cunningham FX, Gantt E (February 2001). "One ring or two? Determination of ring number in carotenoids by lycopene epsilon-cyclases". Proceedings of the National Academy of Sciences of the United States of America. 98 (5): 2905–10. doi:10.1073/pnas.051618398. PMC 30238. PMID 11226339.
  2. Stickforth P, Steiger S, Hess WR, Sandmann G (June 2003). "A novel type of lycopene epsilon-cyclase in the marine cyanobacterium Prochlorococcus marinus MED4". Archives of Microbiology. 179 (6): 409–15. doi:10.1007/s00203-003-0545-4. PMID 12712234.
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