MBOAT7

Lysophospholipid acyltransferase 7 also known as membrane-bound O-acyltransferase domain-containing protein 7 (MBOAT7) is an enzyme that in humans is encoded by the MBOAT7 gene.[5] It is homologous to other membrane-bound O-acyltransferases.

MBOAT7
Identifiers
AliasesMBOAT7, BB1, LENG4, LPIAT, LRC4, MBOA7, OACT7, hMBOA-7, membrane bound O-acyltransferase domain containing 7, MRT57, LPLAT
External IDsOMIM: 606048 MGI: 1924832 HomoloGene: 11510 GeneCards: MBOAT7
EC number2.3.1.n4
Gene location (Human)
Chr.Chromosome 19 (human)[1]
Band19q13.42Start54,173,412 bp[1]
End54,189,882 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

79143

77582

Ensembl

ENSMUSG00000035596

UniProt

Q96N66

Q8CHK3

RefSeq (mRNA)

NM_001146056
NM_001146082
NM_001146083
NM_024298

NM_029934

RefSeq (protein)

NP_001139528
NP_001139554
NP_001139555
NP_077274

NP_084210

Location (UCSC)Chr 19: 54.17 – 54.19 MbChr 7: 3.68 – 3.69 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

This gene encodes a member of the membrane-bound O-acyltransferases family of integral membrane proteins that have acyltransferase activity. The encoded protein is a lysophosphatidylinositol acyltransferase that has specificity for arachidonoyl-CoA as an acyl donor. This protein is involved in the re-acylation of phospholipids as part of the phospholipid remodeling pathway known as the Land cycle.[5]

References

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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