MRPS9

Mitochondrial ribosomal protein S9 (MRPS9), otherwise known as uS9m, is a protein that in humans is encoded by the MRPS9 gene. [5]

MRPS9
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesMRPS9, MRP-S9, RPMS9, S9mt, mitochondrial ribosomal protein S9
External IDsOMIM: 611975 MGI: 1916777 HomoloGene: 32565 GeneCards: MRPS9
Gene location (Human)
Chr.Chromosome 2 (human)[1]
Band2q12.1Start105,038,069 bp[1]
End105,099,960 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

64965

69527

Ensembl

ENSG00000135972

ENSMUSG00000060679

UniProt

P82933

Q9D7N3

RefSeq (mRNA)

NM_182640

NM_023514

RefSeq (protein)

NP_872578

NP_076003

Location (UCSC)Chr 2: 105.04 – 105.1 MbChr 1: 42.85 – 42.91 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. [provided by RefSeq, Jul 2008].

See also

References
  1. GRCh38: Ensembl release 89: ENSG00000135972 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000060679 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: Mitochondrial ribosomal protein S9". Retrieved 2018-02-11.

Further reading
  • Overview of all the structural information available in the PDB for UniProt: P82933 (Human 28S ribosomal protein S9, mitochondrial (MRPS9)) at the PDBe-KB.

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