Martin Kreitman

Kreitman graduated from Stony Brook University with a Bachelor of Science degree Biology in 1975, and from the University of Florida with a Master of Science degree in Zoology, in 1977. He went on to study at Harvard University, graduating with a Ph.D. in Population Genetics, specifically Nucleotide Sequence Variation of Alcohol dehydrogenase in Drosophila melanogaster[6] in 1983.[7]

The Kreitman lab does research in four main areas:[8][9][10][11]

"Functional evolution of cis-regulatory sequences (Drosophila)"[12]

"Molecular population genetics and evolution (Drosophila and Arabidopsis)"[12]

"Canalization in development and evolution (Drosophila)"[12]

"Evolutionary dynamics of disease resistance and pathogenicity (Arabidopsis)"[12]

• 1991 MacArthur Fellows Program
• editor-in-chief of "Journal of Molecular Evolution" from 1999
• Section head of the "Evolutionary/Comparative Genetics" part of Faculty of 1000 biology [13]
• 2010 named fellow of the American Academy of Arts and Sciences [14]

• Ludwig, M. Z.; Manu; Kittler, R.; White, K. P.; Kreitman, M. (2011). Malik, Harmit S (ed.). "Consequences of Eukaryotic Enhancer Architecture for Gene Expression Dynamics, Development, and Fitness". PLOS Genetics. 7 (11): e1002364. doi:10.1371/journal.pgen.1002364. PMC 3213169. PMID 22102826.
• He, B. Z.; Holloway, A. K.; Maerkl, S. J.; Kreitman, M. (2011). Petrov, Dmitri A (ed.). "Does Positive Selection Drive Transcription Factor Binding Site Turnover? A Test with Drosophila Cis-Regulatory Modules". PLOS Genetics. 7 (4): e1002053. doi:10.1371/journal.pgen.1002053. PMC 3084208. PMID 21572512.
• Lott, S. E.; Ludwig, M. Z.; Kreitman, M. (2011). "Evolution and Inheritance of Early Embryonic Patterning in Drosophila Simulans and D. Sechellia". Evolution. 65 (5): 1388–1399. doi:10.1111/j.1558-5646.2010.01206.x. PMC 3083464. PMID 21121913.
• Bakker, E. G.; Traw, M. B.; Toomajian, C.; Kreitman, M.; Bergelson, J. (2008). "Low Levels of Polymorphism in Genes That Control the Activation of Defense Response in Arabidopsis thaliana". Genetics. 178 (4): 2031–2043. doi:10.1534/genetics.107.083279. PMC 2323794. PMID 18245336.
• Araki, H.; Innan, H.; Kreitman, M.; Bergelson, J. (2007). "Molecular Evolution of Pathogenicity-Island Genes in Pseudomonas viridiflava". Genetics. 177 (2): 1031–1041. doi:10.1534/genetics.107.077925. PMC 2034611. PMID 17720907.
• Lott, S. E.; Kreitman, M.; Palsson, A.; Alekseeva, E.; Ludwig, M. Z. (2007). "Canalization of segmentation and its evolution in Drosophila". Proceedings of the National Academy of Sciences. 104 (26): 10926–10931. Bibcode:2007PNAS..10410926L. doi:10.1073/pnas.0701359104. PMC 1891814. PMID 17569783.
• Bakker, E. G. (2006). "A Genome-Wide Survey of R Gene Polymorphisms in Arabidopsis". The Plant Cell Online. 18 (8): 1803–1818. doi:10.1105/tpc.106.042614. PMC 1533970. PMID 16798885.
• Bakker, E. G.; Stahl, E. A.; Toomajian, C.; Nordborg, M.; Kreitman, M.; Bergelson, J. (2006). "Distribution of genetic variation within and among local populations of Arabidopsis thaliana over its species range". Molecular Ecology. 15 (5): 1405–1418. doi:10.1111/j.1365-294X.2006.02884.x. PMID 16626462.
• Araki, H. (2006). "Presence/absence polymorphism for alternative pathogenicity islands in Pseudomonas viridiflava, a pathogen of Arabidopsis". Proceedings of the National Academy of Sciences. 103 (15): 5887–5892. Bibcode:2006PNAS..103.5887A. doi:10.1073/pnas.0601431103. PMC 1458668. PMID 16581904.
• Nordborg, M.; Hu, T. T.; Ishino, Y.; Jhaveri, J.; Toomajian, C.; Zheng, H.; Bakker, E.; Calabrese, P.; Gladstone, J.; Goyal, R.; Jakobsson, M.; Kim, S.; Morozov, Y.; Padhukasahasram, B.; Plagnol, V.; Rosenberg, N. A.; Shah, C.; Wall, J. D.; Wang, J.; Zhao, K.; Kalbfleisch, T.; Schulz, V.; Kreitman, M.; Bergelson, J. (2005). "The Pattern of Polymorphism in Arabidopsis thaliana". PLOS Biology. 3 (7): e196. doi:10.1371/journal.pbio.0030196. PMC 1135296. PMID 15907155.
• Ludwig, M. Z.; Palsson, A.; Alekseeva, E.; Bergman, C. M.; Nathan, J.; Kreitman, M. (2005). "Functional Evolution of a cis-Regulatory Module". PLOS Biology. 3 (4): e93. doi:10.1371/journal.pbio.0030093. PMC 1064851. PMID 15757364.
• Kreitman, M.; Di Rienzo, A. (2004). "Balancing claims for balancing selection". Trends in Genetics. 20 (7): 300–304. doi:10.1016/j.tig.2004.05.002. PMID 15219394.
• Goss, E. M.; Kreitman, M.; Bergelson, J. (2004). "Genetic Diversity, Recombination and Cryptic Clades in Pseudomonas viridiflava Infecting Natural Populations of Arabidopsis thaliana". Genetics. 169 (1): 21–35. doi:10.1534/genetics.104.031351. PMC 1448860. PMID 15489535.
• Mauricio, R.; Stahl, E. A.; Korves, T.; Tian, D.; Kreitman, M.; Bergelson, J. (2003). "Natural selection for polymorphism in the disease resistance gene Rps2 of Arabidopsis thaliana". Genetics. 163 (2): 735–746. PMC 1462445. PMID 12618410.
• Tian, D.; Traw, M. B.; Chen, J. Q.; Kreitman, M.; Bergelson, J. (2003). "Fitness costs of R-gene-mediated resistance in Arabidopsis thaliana". Nature. 423 (6935): 74–77. Bibcode:2003Natur.423...74T. doi:10.1038/nature01588. PMID 12721627.
• Toomajian, C.; Ajioka, R. S.; Jorde, L. B.; Kushner, J. P.; Kreitman, M. (2003). "A method for detecting recent selection in the human genome from allele age estimates". Genetics. 165 (1): 287–297. PMC 1462736. PMID 14504236.
• Tian, D. (2002). "Signature of balancing selection in Arabidopsis". Proceedings of the National Academy of Sciences. 99 (17): 11525–11530. Bibcode:2002PNAS...9911525T. doi:10.1073/pnas.172203599. PMC 123289. PMID 12172007.
• Toomajian, C.; Kreitman, M. (2002). "Sequence variation and haplotype structure at the human HFE locus". Genetics. 161 (4): 1609–1623. PMC 1462210. PMID 12196404.
• Jakob, K.; Goss, E. M.; Araki, H.; Van, T.; Kreitman, M.; Bergelson, J. (2002). "Pseudomonas viridiflavaandP. Syringae—Natural Pathogens ofArabidopsis thaliana". Molecular Plant-Microbe Interactions. 15 (12): 1195–1203. doi:10.1094/MPMI.2002.15.12.1195. PMID 12481991.
• Comeron, J. M.; Kreitman, M. (2002). "Population, evolutionary and genomic consequences of interference selection". Genetics. 161 (1): 389–410. PMC 1462104. PMID 12019253.
• Nordborg, M.; Borevitz, J. O.; Bergelson, J.; Berry, C. C.; Chory, J.; Hagenblad, J.; Kreitman, M.; Maloof, J. N.; Noyes, T.; Oefner, P. J.; Stahl, E. A.; Weigel, D. (2002). "The extent of linkage disequilibrium in Arabidopsis thaliana". Nature Genetics. 30 (2): 190–193. doi:10.1038/ng813. PMID 11780140.
• Bergman, C. M.; Kreitman, M. (2001). "Analysis of Conserved Noncoding DNA in Drosophila Reveals Similar Constraints in Intergenic and Intronic Sequences". Genome Research. 11 (8): 1335–1345. doi:10.1101/gr.178701. PMID 11483574.
• Bergelson, J.; Kreitman, M.; Stahl, E. A.; Tian, D. (2001). "Evolutionary Dynamics of Plant R-Genes". Science. 292 (5525): 2281–2285. doi:10.1126/science.1061337. PMID 11423651.
• Comeron, J. M.; Kreitman, M. (2000). "The correlation between intron length and recombination in drosophila. Dynamic equilibrium between mutational and selective forces". Genetics. 156 (3): 1175–1190. PMC 1461334. PMID 11063693.
• Ludwig, M. Z.; Bergman, C.; Patel, N. H.; Kreitman, M. (2000). "Evidence for stabilizing selection in a eukaryotic enhancer element". Nature. 403 (6769): 564–567. Bibcode:2000Natur.403..564L. doi:10.1038/35000615. PMID 10676967.
• Bergelson, J.; Stahl, E. A.; Dwyer, G.; Mauricio, R.; Kreitman, M. (1999). "Dynamics of disease resistance polymorphism at the Rpm1 locus of Arabidopsis". Nature. 400 (6745): 667–671. Bibcode:1999Natur.400..667S. doi:10.1038/23260. PMID 10458161.
• Comeron, J. M.; Kreitman, M.; Aguadé, M. (1999). "Natural selection on synonymous sites is correlated with gene length and recombination in Drosophila". Genetics. 151 (1): 239–249. PMC 1460462. PMID 9872963.
• Ludwig, M. Z.; Patel, N. H.; Kreitman, M. (1998). "Functional analysis of eve stripe 2 enhancer evolution in Drosophila: Rules governing conservation and change". Development. 125 (5): 949–958. PMID 9449677.

• "Martin Kreitman", Scientific Commons