Mayo Clinic Florida

Impressed by the medical treatment received by members of Jacksonville's Davis family (then owners of the Winn-Dixie supermarket chain) at the Mayo Clinic in Minnesota, they rallied community and corporate support to bring the Mayo Clinic to Jacksonville and donated the large tract of land off San Pablo Road on which Mayo opened an outpatient consultation center in 1986.[4][2] This was the first time the Mayo Clinic established a location outside of Rochester, Minnesota. With an initial complement of 35 physicians and 145 support personnel, it grew to approximately 5,500 total staff over the following 30 years.[2]

In 1987, Mayo Clinic purchased St. Luke's Hospital, Florida's oldest private hospital (which is also located off J. Turner Butler Boulevard, about 10 miles away from Mayo's San Pablo Road campus) to serve as the admitting hospital for Mayo's Jacksonville location. In 2001, after experiencing significant growth in Jacksonville, Mayo Clinic announced its intention to build a hospital on its San Pablo Road campus. The hospital opened in 2008 and created 304 beds and 22 operating rooms,[1] offering care in more than 35 medical and surgical specialties.[5] Mayo then sold St. Luke's hospital to St. Vincent's HealthCare, which renamed it St. Vincent's Medical Center Southside. Mayo Clinic Hospital is one of three teaching hospitals in Jacksonville, along with UF Health Jacksonville, located in North Jacksonville, and Wolfson Children's Hospital in downtown Jacksonville.

With a $70.5 million expansion plan, more than 300,000 square feet (28,000 m²) of space will be built over the course of five years beginning in 2017.[3] This will allow for the growth of hundreds of staff positions and 100 physicians.[3] The expansion will provide: space for cardiovascular, radiology and cardio-thoracic surgery program areas, expansion of the spine center and pain rehabilitation programs, additional surgical rooms, space and equipment to establish a molecular imaging center for radiology and laboratory expansion.[3] Four new floors will be added to the Mayo-South Building and 40,000 square feet (3,700 m²) in the Davis Building will be remodeled.[11] Three additional buildings will be constructed; one will provide integrated services of complex cancers and have space for neurologic and neurosurgical care, one will be a lung restoration center to allow for more transplantations, and the third will include a positron emission tomography (PET) radiochemistry facility with an on-site cyclotron.[11]

In 2019 Mayo announced it will spend $233 million to create a comprehensive cancer center in its Jacksonville campus. When it opens in 2023 it will be one of only two designated Comprehensive Cancer Centers in Florida.[12] The center will also contain a proton therapy facility, one of three such facilities in Jacksonville (the others being located at UF Health and the Ackerman Cancer Center) and of which there are only a few dozen in the United States.