Neuropixels

Neuropixels probes are electrodes developed in 2017 to record the activity of hundreds of neurons in the brain. The probes are based on CMOS technology and have 1,000 recording sites on a thin, 1-cm long shank.[1] They are used in hundreds of neuroscience laboratories including the International Brain Laboratory, to record brain activity mostly in mice and rats. By revealing the activity of vast numbers of neurons, Neuropixels probes are allowing new approaches[2] to the study of brain processes such as sensory processing, decision making,[3] internal state,[4] and emotions[5] and to create brain-machine interfaces.[6][7] The probes were announced in 2017.[8] They are designed and fabricated by imec, an electronics research center in Belgium.

References

  1. "How to make sense of the brain's billions of neurons | Wellcome". wellcome.ac.uk. Retrieved 2020-08-25.
  2. Hernandez, Daniela (2018-06-15). "The Quest to Decode the Brain". Wall Street Journal. ISSN 0099-9660. Retrieved 2020-08-25.
  3. Steinmetz, Nicholas A.; Zatka-Haas, Peter; Carandini, Matteo; Harris, Kenneth D. (December 2019). "Distributed coding of choice, action and engagement across the mouse brain". Nature. 576 (7786): 266–273. doi:10.1038/s41586-019-1787-x. ISSN 1476-4687. PMC 6913580. PMID 31776518.
  4. Allen, William E.; Chen, Michael Z.; Pichamoorthy, Nandini; Tien, Rebecca H.; Pachitariu, Marius; Luo, Liqun; Deisseroth, Karl (2019-04-19). "Thirst regulates motivated behavior through modulation of brainwide neural population dynamics". Science. 364 (6437). doi:10.1126/science.aav3932. ISSN 0036-8075. PMID 30948440.
  5. Abbott, Alison (2020-08-11). "Inside the mind of an animal". Nature. 584: 182–185. doi:10.1038/d41586-020-02337-x.
  6. "How brains and machines can be made to work together". The Economist. ISSN 0013-0613. Retrieved 2020-08-25.
  7. Markoff, John (2019-07-16). "Elon Musk's Neuralink Wants 'Sewing Machine-Like' Robots to Wire Brains to the Internet". The New York Times. ISSN 0362-4331. Retrieved 2020-08-25.
  8. Jun, James J.; Steinmetz, Nicholas A.; Siegle, Joshua H.; Denman, Daniel J.; Bauza, Marius; Barbarits, Brian; Lee, Albert K.; Anastassiou, Costas A.; Andrei, Alexandru; Aydın, Çağatay; Barbic, Mladen (2017-11-08). "Fully Integrated Silicon Probes for High-Density Recording of Neural Activity". Nature. 551 (7679): 232–236. doi:10.1038/nature24636. ISSN 0028-0836. PMC 5955206. PMID 29120427.
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