Nucleocidin

Nucleocidin is a fluorine-containing nucleoside produced by Streptomyces calvus.[1]

Nucleocidin

Identifiers
CAS Number	24751-69-7
3D model (JSmol)	Interactive image
ChemSpider	65250
PubChem CID	72299
UNII	F5097NG7JT
InChI InChI=1S/C10H13FN6O6S/c11-10(1-22-24(13,20)21)6(19)5(18)9(23-10)17-3-16-4-7(12)14-2-15-8(4)17/h2-3,5-6,9,18-19H,1H2,(H2,12,14,15)(H2,13,20,21)/t5-,6+,9-,10-/m1/s1 Key: LTBCQBSAWAZBDF-MLTZYSBQSA-N
SMILES c1nc(c2c(n1)n(cn2)[C@H]3[C@@H]([C@@H]([C@](O3)(COS(=O)(=O)N)F)O)O)N
Properties
Chemical formula	C10H13FN6O6S
Molar mass	364.31 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

During 1968 the attempts to identify nucleocidin were made and at that time it was assigned to a structure of a 9-adenyl-4' -sulfamoyloxypentofuranoside, which was mainly based on experiments from pmr and mass spectroscopy, as well as testing in chemical reactions. It was ultimately proven to have a structure of a 4' -fluoro-5' -O-sulphamoyladenosine.[2] Nucleocidin is an antibiotic that can be produced from Streptomyces calvus that grows on Indian land. It is essentially toxic for mammals, although nucleocidin is able to function against a bacteria, such as gram negative, and gram positive. Moreover it can be used against trypanosomes.[3]