OSBPL11

Oxysterol-binding protein-related protein 11 is a protein that in humans is encoded by the OSBPL11 gene.[5]

OSBPL11
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesOSBPL11, ORP-11, ORP11, OSBP12, TCCCIA00292, oxysterol binding protein like 11
External IDsOMIM: 606739 MGI: 2146553 HomoloGene: 23385 GeneCards: OSBPL11
Gene location (Human)
Chr.Chromosome 3 (human)[1]
Band3q21.2Start125,528,858 bp[1]
End125,595,497 bp[1]
RNA expression pattern


More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

114885

106326

Ensembl

ENSG00000144909

ENSMUSG00000022807

UniProt

Q9BXB4

Q8CI95

RefSeq (mRNA)

NM_022776

NM_176840

RefSeq (protein)

NP_073613

NP_789810

Location (UCSC)Chr 3: 125.53 – 125.6 MbChr 16: 33.19 – 33.24 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Like most members, the encoded protein contains an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain.[5]

References

  1. GRCh38: Ensembl release 89: ENSG00000144909 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000022807 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: OSBPL11 oxysterol binding protein-like 11".

Further reading

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