PEX11B

Peroxisomal membrane protein 11B is a protein that in humans is encoded by the PEX11B gene.[5][6] It is involved in the regulation of peroxisome abundance. [7]

PEX11B
Identifiers
AliasesPEX11B, PEX11-BETA, PEX14B, peroxisomal biogenesis factor 11 beta
External IDsOMIM: 603867 MGI: 1338882 HomoloGene: 2852 GeneCards: PEX11B
Gene location (Human)
Chr.Chromosome 1 (human)[1]
Band1q21.1Start145,911,350 bp[1]
End145,918,717 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

8799

18632

Ensembl

ENSG00000131779

ENSMUSG00000028102

UniProt

O96011

Q9Z210

RefSeq (mRNA)

NM_001184795
NM_003846

NM_001162387
NM_001162388
NM_011069

RefSeq (protein)

NP_001171724
NP_003837

NP_001155859
NP_001155860
NP_035199

Location (UCSC)Chr 1: 145.91 – 145.92 MbChr 3: 96.64 – 96.65 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse


Interactions

PEX11B has been shown to interact with PEX19.[8][9]

References

  1. GRCh38: Ensembl release 89: ENSG00000131779 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000028102 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Schrader M, Reuber BE, Morrell JC, Jimenez-Sanchez G, Obie C, Stroh TA, Valle D, Schroer TA, Gould SJ (December 1998). "Expression of PEX11beta mediates peroxisome proliferation in the absence of extracellular stimuli". J Biol Chem. 273 (45): 29607–14. doi:10.1074/jbc.273.45.29607. PMID 9792670.
  6. "Entrez Gene: PEX11B peroxisomal biogenesis factor 11B".
  7. Thoms S, Erdmann R (October 2005). "Dynamin-related proteins and Pex11 proteins in peroxisome division and proliferation". FEBS J. 272 (20): 5169–81. doi:10.1111/j.1742-4658.2005.04939.x. PMID 16218949.
  8. Sacksteder, K A; Jones J M; South S T; Li X; Liu Y; Gould S J (March 2000). "Pex19 Binds Multiple Peroxisomal Membrane Proteins, Is Predominantly Cytoplasmic, and Is Required for Peroxisome Membrane Synthesis". J. Cell Biol. 148 (5): 931–44. doi:10.1083/jcb.148.5.931. ISSN 0021-9525. PMC 2174547. PMID 10704444.
  9. Fransen, M; Wylin T; Brees C; Mannaerts G P; Van Veldhoven P P (July 2001). "Human Pex19p Binds Peroxisomal Integral Membrane Proteins at Regions Distinct from Their Sorting Sequences". Mol. Cell. Biol. 21 (13): 4413–24. doi:10.1128/MCB.21.13.4413-4424.2001. ISSN 0270-7306. PMC 87101. PMID 11390669.

Further reading


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