Protoporphyrinogen IX dehydrogenase (menaquinone)
Protoporphyrinogen IX dehydrogenase (menaquinone) (EC 1.3.5.3, HemG) is an enzyme with systematic name protoporphyrinogen IX:menaquinone oxidoreductase.[1] This enzyme catalyses the following chemical reaction
- protoporphyrinogen IX + 3 menaquinone protoporphyrin IX + 3 menaquinol
| Protoporphyrinogen IX dehydrogenase (menaquinone) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.3.5.3 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
This enzyme enables Escherichia coli to synthesize heme in both aerobic and anaerobic environments.
References
- Boynton TO, Daugherty LE, Dailey TA, Dailey HA (July 2009). "Identification of Escherichia coli HemG as a novel, menadione-dependent flavodoxin with protoporphyrinogen oxidase activity". Biochemistry. 48 (29): 6705–11. doi:10.1021/bi900850y. PMC 2749469. PMID 19583219.
External links
- Protoporphyrinogen+IX+dehydrogenase+(menaquinone) at the US National Library of Medicine Medical Subject Headings (MeSH)
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