Putrescine aminotransferase
Putrescine aminotransferase (EC 2.6.1.82, putrescine-alpha-ketoglutarate transaminase, YgjG, putrescine:alpha-ketoglutarate aminotransferase, PAT, putrescine:2-oxoglutarate aminotransferase, putrescine transaminase) is an enzyme with systematic name butane-1,4-diamine:2-oxoglutarate aminotransferase.[1][2][3] This enzyme catalyses the following chemical reaction
- putrescine + 2-oxoglutarate 1-pyrroline + L-glutamate + H2O (overall reaction)
- (1a) putrescine + 2-oxoglutarate 4-aminobutanal + L-glutamate
- (1b) 4-aminobutanal 1-pyrroline + H2O (spontaneous)
| Putrescine aminotransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.6.1.82 | ||||||||
| CAS number | 98982-73-1 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
This enzyme is a pyridoxal-phosphate protein.
References
- Prieto-Santos MI, Martín-Checa J, Balaña-Fouce R, Garrido-Pertierra A (February 1986). "A pathway for putrescine catabolism in Escherichia coli". Biochimica et Biophysica Acta (BBA) - General Subjects. 880 (2–3): 242–4. doi:10.1016/0304-4165(86)90085-1. PMID 3510672.
- Samsonova NN, Smirnov SV, Novikova AE, Ptitsyn LR (August 2005). "Identification of Escherichia coli K12 YdcW protein as a gamma-aminobutyraldehyde dehydrogenase". FEBS Letters. 579 (19): 4107–12. doi:10.1016/j.febslet.2005.06.038. PMID 16023116.
- Samsonova NN, Smirnov SV, Altman IB, Ptitsyn LR (January 2003). "Molecular cloning and characterization of Escherichia coli K12 ygjG gene". BMC Microbiology. 3 (1): 2. doi:10.1186/1471-2180-3-2. PMC 150594. PMID 12617754.
External links
- Putrescine+aminotransferase at the US National Library of Medicine Medical Subject Headings (MeSH)
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