Quinoline-4-carboxylate 2-oxidoreductase
In enzymology, a quinoline-4-carboxylate 2-oxidoreductase (EC 1.3.99.19) is an enzyme that catalyzes the chemical reaction
- quinoline-4-carboxylate + acceptor + H2O 2-oxo-1,2-dihydroquinoline-4-carboxylate + reduced acceptor
| quinoline-4-carboxylate 2-oxidoreductase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.3.99.19 | ||||||||
| CAS number | 175780-18-4 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
The 3 substrates of this enzyme are quinoline-4-carboxylate, acceptor, and H2O, whereas its two products are 2-oxo-1,2-dihydroquinoline-4-carboxylate and reduced acceptor.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with other acceptors. The systematic name of this enzyme class is quinoline-4-carboxylate:acceptor 2-oxidoreductase (hydroxylating). Other names in common use include quinaldic acid 4-oxidoreductase, and quinoline-4-carboxylate:acceptor 2-oxidoreductase (hydroxylating).
References
- Bauer G, Lingens F (1992). "Microbial metabolism of quinoline and related compounds. XV Quinoline-4-carboxylic acid oxidoreductase from Agrobacterium spec.1B: a molybdenum-containing enzyme". Biol. Chem. Hoppe-Seyler. 373 (8): 699–705. doi:10.1515/bchm3.1992.373.2.699. PMID 1418685.
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