RADIL

RADIL
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1UM1, 3EC8
Identifiers
Aliases	RADIL, RASIP2, Rap associating with DIL domain
External IDs	OMIM: 611491 MGI: 2443088 HomoloGene: 77648 GeneCards: RADIL
Gene location (Human)
Chr.	Chromosome 7 (human)[1]
End	4,883,716 bp[1]
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)[2]
End	142,551,098 bp[2]
RNA expression pattern
	More reference expression data
Gene ontology
Molecular function	• GO:0001948 protein binding;
Cellular component	• microtubules; • macromolecular complex;
Biological process	• multicellular organism development; • substrate adhesion-dependent cell spreading; • cell adhesion; • signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	55698
	231858
	ENSG00000157927
	ENSMUSG00000029576
	Q96JH8
	Q69Z89
	NM_018059
	NM_001289588; NM_178702; NM_001310752
	NP_060529
	NP_001276517; NP_001297681; NP_848817
	Wikidata
View/Edit Human	View/Edit Mouse

Ras-associating and dilute domain-containing protein is a protein that in humans is encoded by the RADIL gene.[5][6][7]

References

GRCh38: Ensembl release 89: ENSG00000157927 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000029576 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Zhang Z, Rehmann H, Price LS, Riedl J, Bos JL (Sep 2005). "AF6 negatively regulates Rap1-induced cell adhesion". J Biol Chem. 280 (39): 33200–5. doi:10.1074/jbc.M505057200. PMID 16051602.
Smolen GA, Schott BJ, Stewart RA, Diederichs S, Muir B, Provencher HL, Look AT, Sgroi DC, Peterson RT, Haber DA (Sep 2007). "A Rap GTPase interactor, RADIL, mediates migration of neural crest precursors". Genes Dev. 21 (17): 2131–6. doi:10.1101/gad.1561507. PMC 1950852. PMID 17704304.
"Entrez Gene: FLJ10324 hypothetical protein FLJ10324".

Ahmed SM, Daulat AM, Meunier A, Angers S (February 2010). "G protein betagamma subunits regulate cell adhesion through Rap1a and its effector Radil". J. Biol. Chem. 285 (9): 6538–51. doi:10.1074/jbc.M109.069948. PMC 2825450. PMID 20048162.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
Nagase T, Nakayama M, Nakajima D, et al. (2001). "Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 8 (2): 85–95. doi:10.1093/dnares/8.2.85. PMID 11347906.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7". Nature. 424 (6945): 157–64. doi:10.1038/nature01782. PMID 12853948.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Brandenberger R, Wei H, Zhang S, et al. (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation". Nat. Biotechnol. 22 (6): 707–16. doi:10.1038/nbt971. PMID 15146197. S2CID 27764390.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.

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[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000157927 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000029576 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid16051602-5] Zhang Z, Rehmann H, Price LS, Riedl J, Bos JL (Sep 2005). "AF6 negatively regulates Rap1-induced cell adhesion". J Biol Chem. 280 (39): 33200–5. doi:10.1074/jbc.M505057200. PMID 16051602.

[pmid17704304-6] Smolen GA, Schott BJ, Stewart RA, Diederichs S, Muir B, Provencher HL, Look AT, Sgroi DC, Peterson RT, Haber DA (Sep 2007). "A Rap GTPase interactor, RADIL, mediates migration of neural crest precursors". Genes Dev. 21 (17): 2131–6. doi:10.1101/gad.1561507. PMC 1950852. PMID 17704304.

[entrez-7] "Entrez Gene: FLJ10324 hypothetical protein FLJ10324".

RADIL

References

Further reading