RALY

RNA-binding protein Raly is a protein that in humans is encoded by the RALY gene.[5][6]

RALY
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesRALY, HNRPCL2, P542, RALY heterogeneous nuclear ribonucleoprotein
External IDsOMIM: 614663 MGI: 97850 HomoloGene: 7216 GeneCards: RALY
Gene location (Human)
Chr.Chromosome 20 (human)[1]
Band20q11.22Start33,993,646 bp[1]
End34,108,308 bp[1]
RNA expression pattern


More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

22913

19383

Ensembl

ENSG00000125970

ENSMUSG00000027593

UniProt

Q9UKM9

Q64012

RefSeq (mRNA)

NM_007367
NM_016732

NM_001139511
NM_001139512
NM_001139513
NM_023130

RefSeq (protein)

NP_031393
NP_057951

NP_001132983
NP_001132984
NP_001132985
NP_075619

Location (UCSC)Chr 20: 33.99 – 34.11 MbChr 2: 154.79 – 154.87 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

In infectious mononucleosis, anti-EBNA-1 antibodies are produced which cross-react with multiple normal human proteins. The cross-reactivity is due to anti-gly/ala antibodies that cross-react with host proteins containing configurations like those in the EBNA-1 repeat. One such antigen is RALY which is a member of the heterogeneous nuclear ribonucleoprotein gene family.[6]


References

  1. GRCh38: Ensembl release 89: ENSG00000125970 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000027593 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Khrebtukova I, Kuklin A, Woychik RP, Michaud EJ (Nov 1999). "Alternative processing of the human and mouse raly genes(1)". Biochim Biophys Acta. 1447 (1): 107–12. doi:10.1016/s0167-4781(99)00126-8. PMID 10500250.
  6. "Entrez Gene: RALY RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse))".

Further reading


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