RB-3007

RB-3007 is an orally active analogue of RB-101. It acts as an enkephalinase inhibitor, which is used in scientific research.[1][2]

RB-3007
Names
IUPAC name
Benzyl (2S)-2-[[(2S)-2-[[2-acetylsulfanylethoxy-[(R)-amino(phenyl)methyl]phosphoryl]methyl]-3-(4-phenylphenyl)propanoyl]amino]propanoate
Other names
RB3007, LS-15768
Identifiers
3D model (JSmol)
Properties
C37H41N2O6PS
Molar mass 672.78 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

See also
  • RB-101 - enkephalinase inhibitor that produces analgesia without respiratory depression
  • D/DL-Phenylalanine - D-phenylalanine blockage of enkephalin degradation may be responsible for the reputed analgesic effect of DL-Phenylalanine
  • Racecadotril - an antidiarrheal drug which acts as a peripheral enkephalinase inhibitor
  • Ecadotril - a neutral endopeptidase inhibitor

References
  1. Thanawala, V.; Kadam, V.; Ghosh, R. (1 October 2008). "Enkephalinase Inhibitors: Potential Agents for the Management of Pain". Current Drug Targets. 9 (10): 887–894. doi:10.2174/138945008785909356. PMID 18855623.
  2. Noble, Florence; Roques, Bernard P (17 January 2007). "Protection of endogenous enkephalin catabolism as natural approach to novel analgesic and antidepressant drugs". Expert Opinion on Therapeutic Targets. 11 (2): 145–159. doi:10.1517/14728222.11.2.145. PMID 17227231.
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