Rizzoli & Isles

• Angie Harmon as Jane Clementine Rizzoli: a Boston detective in the Homicide Unit. From an Italian American family, Jane is brash, sarcastic, and often prickly but also a confident and independent woman as well as a brilliant detective. She is the tomboy daughter of an overprotective mother. She is extremely competitive, especially with her younger brother, Frankie (also a cop), who is often caught in her shadow. Jane can tackle a perp like a linebacker. She rarely lets her guard down with anyone, except her best friend, Maura Isles. She is something of a slob; her apartment has been shown on several occasions to be quite messy, and in one episode she claimed to have just opened a box of cereal five years after originally buying it. As a child, she was slightly chubby, earning her the nickname "Roly-Poly Rizzoli". She mentioned in one episode that she played field hockey as an attacker in junior college. She is the eldest Rizzoli sibling,[3] and graduated from high school in 1994, which puts Jane's birth year at 1976.[4] She is hopeless with men and allergic to dogs, but she winds up taking in Jo Friday, a stray dog rescued by her former partner, Korsak. Raised in the blue-collar Boston suburb of Revere, Jane has fought long and hard to win the respect of her colleagues, but it is her relationship with her equally stubborn mother, Angela Rizzoli, that sometimes proves to be her biggest headache. During her time on the force, she had a traumatic experience at the hands of a serial killer known as "The Surgeon", Charles Hoyt. While trying to rescue one of his victims, she was taken by surprise from behind and almost became a victim herself. She has matching scars in the center of her palms where Hoyt stabbed her with scalpels, keeping her pinned to the ground. Her original partner, Vince Korsak, saved her life, and Jane survived the brutal, near-death attack by Hoyt. Although she put Hoyt behind bars, she is still haunted by him. She learned that she was pregnant at the end of season four, owing to a liaison with her old boyfriend Casey, but lost the baby midway through the fifth season when she was attacked while protecting a key witness in a case. In the final season, Jane takes a new job as an instructor at the FBI Academy in Quantico, Virginia, and works her final case with the Boston PD in the series finale, "Ocean-Frank".
• Sasha Alexander as Dr. Maura Dorothea Isles: the Commonwealth of Massachusetts' Chief Medical Examiner. Isles is a forensic expert working at the Boston Police Department and Jane's best friend. Maura is a walking encyclopedia, able to spout out facts regardless of whether or not they are relevant to a case. She has a pet tortoise named Bass, after noted forensic anthropologist William M. Bass. Maura is not easily ruffled and has a steady temperament. She absolutely loves examining dead bodies, but she has a tendency to diagnose living people a little too often. She is the adopted only child of a wealthy family. In high school, she was nicknamed "Maura-The-Bore-A" because her classmates thought she was boring. She is always impeccably dressed and is known around the force as "Queen of the Dead"; her ring tone on Jane's phone appropriately plays Chopin's "Funeral March". Maura is the complete opposite of Jane, though they are best friends. Though Maura is socially awkward and has trouble with men because of her brutal honesty and habit of revealing all their medical conditions, she is not awkward around Jane. She can analyze x-rays and blood chemistries and can slice open muscles and organs but possesses no scalpel with which to dissect human emotions. Maura also cannot lie; if she does, she breaks out in hives. It is later revealed that her biological father is an Irish crime boss named Paddy Doyle, something she finds out while investigating her half-brother's death. She finds out in the episode "What Doesn't Kill You" (3.1) that her father told her biological mother that she died on the day she was born, August 7, 1976. She subsequently visited a cemetery containing a gravestone with the name "Baby Maura Doyle" on it. In the series finale, "Ocean-Frank", Maura takes a sabbatical from the ME's office to go to Paris, France, and work on her novel.
• Lorraine Bracco as Angela Rizzoli: Jane, Frankie and Tommy's overbearing mother. Angela is fiercely protective of her children, saying she has not slept since Jane decided to become a cop. Angela wishes Jane could be a little more feminine and is constantly trying to set her up on dates. After her divorce, she spent some time working in the precinct's café, and dated Lieutenant Cavanagh, but she quit the job and broke up with Cavanagh when she decided that she needed to re-evaluate her life. She currently works at the bar that Vince Korsak bought and that they all frequent.
• Bruce McGill as Vincent "Vince" Walter Korsak: Rizzoli's former partner. The two maintain a close bond after years of working together, but Korsak is clearly bothered that he is no longer partnered with Jane. He seems to care for her like a daughter and is nearly as protective of her as Angela is. It is revealed in the series pilot that he saved her life from Hoyt. He will drop whatever he is doing on a moment's notice to rescue an animal, and enjoys watching videos of dogs on the Internet. After remaining a detective for nearly his entire career, Korsak was finally promoted to sergeant-detective in season two, and took the lieutenant's exam in season five. In preparing for retirement, Vince bought the local bar that they all frequent, the Dirty Robber, and employed Angela. He was a US Marine and served during the Vietnam War. Korsak has been divorced 3 times, despite the jokes that he is behind the times he is very wise and observant. He also has several hobbies including playing guitar and sailing, Maura has even once before asked him for his expertise on seaman knots and skills. In the series finale "Ocean-Frank", Korsak retires from the Boston PD after a thirty-two year career.
• Lee Thompson Young as Barold "Barry" Frost (seasons 1–4): Rizzoli's second partner. A whiz when it comes to computers and technology, he is terrified of dead bodies and becomes ill at the sight of blood. He is very protective of Jane and stands by her like a loyal, tough partner. In the season five premiere, he is killed off in a car accident while returning from vacation, due in part to the actor's suicide by gunshot in 2013. In the season five finale, the team establish the Barry Frost Memorial Scholarship, intended for students who are academically gifted and seek to go into professions that would help others but lack the resources to do so.
• Jordan Bridges as Francesco "Frankie" Rizzoli, Jr.: Jane's brother and police officer. He looks up to Jane, but does not like feeling caught in her shadow, especially as he tries to make his own way on the police force. Like all the men in Jane's life, Frankie is more protective of Jane than she would like. He is a cop against his mother's wishes, and sees his sister as a role model. In season four, Frankie is promoted to detective and starts taking night classes in computer science in season five to increase his skill set in Frost's absence. In season seven, he begins a romantic relationship with Nina and eventually successfully proposes to her.
• Brian Goodman as Sean Cavanaugh (main, seasons 3–4; recurring, seasons 1–2, 5): the lieutenant of the Boston PD's Homicide Unit. Fiercely loyal to Jane and an old friend of Korsak, Sean is willing to bend the rules for his guys. It is later discovered that Sean lost his wife and son in a fire (set by Paddy Doyle) back when he and Korsak were rookies.
• Idara Victor as Nina Holiday (main, seasons 6–7; recurring, season 5): a crime scene analyst and computer technician. Formerly a detective, Holiday transferred to Boston Homicide in order to hone her analytical skills in an office-based environment.[5] Following her being shot in the sixth-season finale, Frankie Rizzoli begins a romantic relationship with her and later successfully proposes to her in the seventh.
• Adam Sinclair as Dr. Kent Drake (main, season 7; recurring, season 6): a lab technician, and Maura's new assistant starting in the sixth season. In the series finale, "Ocean-Frank", Kent is set to oversee the Commonwealth of Massachusetts' Medical Examiner's Office during Maura's sabbatical.

• Annabeth Gish as Alice Sands. Alice was born into a distinguished law enforcement family, but she dropped out of the police academy while Jane was enrolled. Alice was second in her class behind Jane, after having been the best at everything prior to then. This created her dangerous fixation on Jane, which led to Alice inserting herself into a circle of tunnel residents and having them do her bidding upon turning to a life of crime and ending up arrested. After being released, Alice began her revenge plans on Jane. Following a shootout at Korsak's wedding reception, Jane seems to make a personal vendetta against Alice. Jane ultimately corners Alice, who has taken a teenager hostage, and shoots her dead. This leaves her team to wonder if Jane shot her in the line of duty or an act of vengeance.
• Tina Huang as Susie Chang, the senior criminalist of the Boston Police Department's crime laboratory. She has described herself as having a very physical memory; when circumstances required her to take point in an investigation, she made various dioramas to explain her reasoning. In the third-season episode "Class Action Satisfaction", she is revealed to be a nudist. She was killed in the sixth-season episode "Misconduct" as part of a complex plan to frame the forensics department for poor handling of a recent case, but the subsequent investigation exposed the killer's true agenda.
• Brian Dennehy as Detective Kenny Leahy.
• Donnie Wahlberg as Lieutenant Joe Grant, an old rival of Jane's who has known her since childhood. He constantly made fun of her, calling her "Frog-Face" and "Roly-Poly Rizzoli" because she was slightly chubby when she was younger. When he leaves for Washington, DC after being appointed as the liaison between Boston and Homeland Security, he claims that he had liked her for a very long time.
• John Doman as Patrick "Paddy" Doyle, an Irish-American crime boss and biological father and protector of Maura Isles. Paddy claimed Maura had died as a baby and made sure she was adopted.[6]
• Jacqueline Bisset as Constance Isles, a visual artist and the adoptive mother of Dr. Maura Isles. She loves Maura but is sorry that they don't have a close relationship.
• Colin Egglesfield as Thomas "Tommy" Rizzoli: the younger brother of Jane and Frankie; he is the youngest of the Rizzoli kids, convicted for running over a priest in a crosswalk on his third DUI violation. He returns to the family fold following his release from prison. As of the season two episode "He Ain't Heavy, He's My Brother", he is 32 years old. He tries to kiss Maura when he comes back to pay her back for her kindness, but she stops him and he develops a crush on Maura as he works on starting a new life.[7]
• Chris Vance as Charles (Casey) Jones, an old flame of Jane's during high school, reunited with Jane during season two. A US Army officer assigned to the Middle East, he returns to Boston in season three but breaks up with Jane because of injuries that left him partially paralyzed below the waist. He returns in season four's first episode after a successful operation and proposes to Jane, but when he receives the offer of a promotion to colonel, he decides to stay in the army, leaving Jane behind as she was unwilling to leave her life. He is aware that Jane was pregnant with his child, but respects her decision to raise the child alone as he had also made the choice to return to the army; she loses the baby midway through the fifth season after being attacked while protecting a witness.
• Darryl Alan Reed as Rondo, a man with access to information in the criminal world. Although Jane initially dismisses his offer to be her confidential informant, he does become her informant later on and is currently providing Jane with information from the criminal world. He has also been shown to have a comical character persona, similar to Larry Laffer. He frequently hits on Jane, calling her "Vanilla", and eventually develops a friendship with Angela, referring to her as "Mrs. Vanilla". He is revealed to be an ex–jazz singer in "This Is How a Heart Breaks".
• Billy Burke as Gabriel Dean, an FBI agent often seen working with the Boston Homicide detectives and Medical Examiner's Office. He later becomes romantically involved with Detective Jane Rizzoli, but she ends this relationship when he tries to use her as part of a plan to capture Paddy Doyle that forced Jane to shoot Paddy.
• Chazz Palminteri as Francesco "Frank" Rizzoli Sr. – Jane, Frankie, and Tommy's father. He owns and runs a plumbing business called Rizzoli and Sons. He and Angela separate and then divorce after the first season. He later tries to have their marriage annulled so that he can remarry in a Catholic ceremony. He returns to announce he has stage 2 prostate cancer, and, despite the news, his family finds it difficult to overlook his past transgressions.
• Matthew Del Negro as Giovanni Gilberti, a dim-witted former classmate of Jane's and a blue-collar auto mechanic. He is under the impression that Maura and Jane are dating, which Maura came up with in order to save the two of them from Giovanni's advances.
• Michael Massee as Charles Hoyt, a former serial killer who kidnapped and stabbed Jane in both hands and continues to threaten Jane, even from behind bars. Hoyt appears in many episodes, including "See One, Do One, Teach One" (episode 1), "I'm Your Boogie Man", and "Remember Me". In the episode "See One, Do One, Teach One", Hoyt and the apprentice he went to medical school with kidnap Jane. Jane shoots and kills the apprentice and throws a flare at Hoyt. Jane then shoots him in the hands and says, "We match". In the episode "Remember Me", Hoyt, despite dying of cancer, lures Jane and Maura into his hospital room with the aid of a new apprentice with the goal of killing Jane before he dies, but Jane manages to get the upper hand and stabs and kills Hoyt with a scalpel while saying, "I win". Despite his death, he continues to haunt Jane and the team and was mentioned in the next two seasons after his death; when dealing with the murders committed by Dennis Rockmond ("Melt My Heart of Stone"), Jane speculates that he may be an apprentice of Hoyt's due to the ritualistic nature of his crimes, and "No One Mourns the Wicked" saw the team deal with a forensic pathologist and her son (conceived by her father's abuse) who were committing murders inspired by Hoyt's methods.
• Sharon Lawrence as Hope Martin, Maura's biological mother, who believed Maura died as a baby. She is a noted forensic pathologist.
• Emilee Wallace as Cailin Martin, Hope's daughter and Maura's half-sister. Maura anonymously donated her kidney to Cailin to save her life.
• Alexandra Holden as Lydia Sparks, a ditzy young woman who is heavily pregnant when she is befriended by Angela. It is soon revealed that the child she is carrying is either Tommy's or Angela's ex-husband Frank's. Eventually the child is known as TJ, for "Tommy Junior", once a test confirms that Tommy is the father.
• Jaz Sinclair as Tasha Williams.

Rizzoli & Isles is available to stream on WarnerMedia's HBO Max, which launched on May 27, 2020.

The series started strong in the ratings, as 7.55 million viewers tuned in for the premiere episode. Rizzoli & Isles was the second most-watched cable program on the evening of July 12, 2010, behind its lead-in, The Closer, which had 110,000 more viewers.[49] The show finished the week in third behind The Closer and the final episode of Deadliest Catch.[50]

The premiere set a record as the highest-rated debut for a commercial-supported cable series, and it was the second-highest debut ever for a basic cable TV series.[51][52] Rizzoli & Isles is second only to the 2008 premiere of Raising the Bar, which attracted 7.7 million viewers during its commercial-free debut.[52][53][54] Live + 7 day ratings for the premiere updated the show's status as the all-time most-watched cable series launch, with DVR viewers increasing the show's rating to just over 9 million viewers.[55]

The show has ranked in the top five cable programs all five seasons and was the number one basic cable program in its fifth season.[56]

The show has been described as having lesbian undertones,[57][58][59] and the purported sexual attraction between Rizzoli and Isles has been the subject of critical and fan attention,[60][61][62][59][63] with sites such as The Advocate connecting the show's lesbian subtext to its popularity.[64] Harmon said that she was not surprised by the attention[65] and that, while it was "'super fun' to play a role that has some same-sex romantic vibes", the characters are "straight" and "just best friends".[60] Alexander said that she was not initially aware of the subtext but believed it reflected the characters' chemistry.[66] She also expressed skepticism that Rizzoli and Isles' friendship was out of the ordinary.[67]