SFSWAP

Splicing factor, suppressor of white-apricot homolog is a protein in humans that is encoded by the SFSWAP gene.[5]

SFSWAP
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesSFSWAP, SFRS8, SWAP, splicing factor SWAP homolog, splicing factor SWAP
External IDsOMIM: 601945 MGI: 101760 HomoloGene: 134548 GeneCards: SFSWAP
Gene location (Human)
Chr.Chromosome 12 (human)[1]
Band12q24.33Start131,711,081 bp[1]
End131,799,737 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

6433

231769

Ensembl

ENSG00000061936

ENSMUSG00000029439

UniProt

Q12872

Q3USH5

RefSeq (mRNA)

NM_001261411
NM_004592
NM_152235

RefSeq (protein)

NP_001248340
NP_004583

NP_758480
NP_001346881
NP_001365844
NP_001365845
NP_001365846

Location (UCSC)Chr 12: 131.71 – 131.8 MbChr 5: 129.5 – 129.57 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

This gene encodes a human homolog of Drosophila splicing regulatory protein. This gene autoregulates its expression by control of splicing of its first two introns. In addition, it also regulates the splicing of fibronectin and CD45 genes. Two transcript variants encoding different isoforms have been identified.[5]

References

  1. GRCh38: Ensembl release 89: ENSG00000061936 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000029439 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: Splicing factor, suppressor of white-apricot homolog (Drosophila)". Retrieved 2013-05-08.
  • PDBe-KB provides an overview of all the structure information available in the PDB for Human Splicing factor, suppressor of white-apricot homolog (SFSWAP)
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.