SPRY1

Protein sprouty homolog 1 is a protein that in humans is encoded by the SPRY1 gene.[5][6][7]

SPRY1
Identifiers
AliasesSPRY1, hsprouty RTK signaling antagonist 1
External IDsOMIM: 602465 MGI: 1345139 HomoloGene: 4266 GeneCards: SPRY1
Gene location (Human)
Chr.Chromosome 4 (human)[1]
Band4q28.1Start123,396,795 bp[1]
End123,403,760 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

10252

24063

Ensembl

ENSG00000164056

ENSMUSG00000037211

UniProt

O43609

Q9QXV9

RefSeq (mRNA)

NM_001258038
NM_001258039
NM_005841
NM_199327
NM_001375410

NM_011896
NM_001305440
NM_001305441
NM_001305442

RefSeq (protein)

NP_001244967
NP_001244968
NP_005832
NP_955359
NP_001362339

NP_001292369
NP_001292370
NP_001292371
NP_036026

Location (UCSC)Chr 4: 123.4 – 123.4 MbChr 3: 37.64 – 37.64 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse


See also

References

  1. GRCh38: Ensembl release 89: ENSG00000164056 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000037211 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Hacohen N, Kramer S, Sutherland D, Hiromi Y, Krasnow MA (January 1998). "sprouty encodes a novel antagonist of FGF signaling that patterns apical branching of the Drosophila airways". Cell. 92 (2): 253–63. doi:10.1016/S0092-8674(00)80919-8. PMID 9458049. S2CID 498977.
  6. Haglund K, Schmidt MH, Wong ES, Guy GR, Dikic I (July 2005). "Sprouty2 acts at the Cbl/CIN85 interface to inhibit epidermal growth factor receptor downregulation". EMBO Reports. 6 (7): 635–41. doi:10.1038/sj.embor.7400453. PMC 1369112. PMID 15962011.
  7. "Entrez Gene: SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)".

Further reading

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