SSC4D

Scavenger receptor cysteine rich family member with 4 domains is a protein that in humans is encoded by the SSC4D gene. [5]

SSC4D
Identifiers
AliasesSSC4D, S4D-SRCRB, SRCRB-S4D, SRCRB4D, scavenger receptor cysteine rich family member with 4 domains
External IDsOMIM: 607639 MGI: 1924709 HomoloGene: 34137 GeneCards: SSC4D
Gene location (Human)
Chr.Chromosome 7 (human)[1]
Band7q11.23Start76,389,334 bp[1]
End76,409,697 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

136853

109267

Ensembl

ENSG00000146700

ENSMUSG00000029699

UniProt

Q8WTU2

A1L0T3

RefSeq (mRNA)

NM_080744

NM_001160366

RefSeq (protein)

NP_542782

NP_001153838

Location (UCSC)Chr 7: 76.39 – 76.41 MbChr 5: 135.96 – 135.97 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

The scavenger receptor cysteine-rich (SRCR) superfamily is an ancient and highly conserved group of cell surface and/or secreted proteins, some of which are involved in the development of the immune system and the regulation of both innate and adaptive immune responses. Group B SRCR domains usually contain 8 regularly spaced cysteines that give rise to a well-defined intradomain disulfide-bond pattern.

References
  1. GRCh38: Ensembl release 89: ENSG00000146700 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000029699 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: Scavenger receptor cysteine rich family member with 4 domains". Retrieved 2016-09-05.

Further reading
  • Padilla O, Pujana MA, López-de la Iglesia A, Gimferrer I, Arman M, Vilà JM, Places L, Vives J, Estivill X, Lozano F (2002). "Cloning of S4D-SRCRB, a new soluble member of the group B scavenger receptor cysteine-rich family (SRCR-SF) mapping to human chromosome 7q11.23". Immunogenetics. 54 (9): 621–34. doi:10.1007/s00251-002-0507-z. PMID 12466895. S2CID 731351.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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