Salinispora tropica
Salinispora tropica is an obligate marine actinomycetes bacterium species. It produces salinosporamide A and salinosporamide B, potential anti-cancer agents,[1][2][3] as well as the polycyclic macrolides sporolide A and B.[4] The type strain is CNB-440T (= ATCC BAA-916T = DSM 44818T).
| Salinispora tropica | |
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| Species: | S. tropica |
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| Salinispora tropica Maldonado et al. 2005 | |
References
- Fenical, W.; Jensen, P.R.; Palladino, M.A.; Lam, K.S.; Lloyd, G.K.; Potts, B.C. (2009). "Discovery and development of the anticancer agent salinosporamide A (NPI-0052)". Bioorganic & Medicinal Chemistry. 17 (6): 2175–2180. doi:10.1016/j.bmc.2008.10.075. PMC 2814440. PMID 19022674.
- Maldonado, L. A. (2005). "Salinispora arenicola gen. nov., sp. nov. and Salinispora tropica sp. nov., obligate marine actinomycetes belonging to the family Micromonosporaceae". International Journal of Systematic and Evolutionary Microbiology. 55 (5): 1759–1766. doi:10.1099/ijs.0.63625-0. ISSN 1466-5026. PMID 16166663.
- Williams PG; Buchanan GO; Feling RH; Kauffman CA; Jensen PR; Fenical W (August 2005). "New cytotoxic salinosporamides from the marine Actinomycete Salinispora tropica". The Journal of Organic Chemistry. 70 (16): 6196–203. doi:10.1021/jo050511+. PMID 16050677.
- Buchanan, Greg O.; Williams, Philip G.; Feling, Robert H.; Kauffman, Christopher A.; Jensen, Paul R.; Fenical, William (2005). "Sporolides a and b: Structurally Unprecedented Halogenated Macrolides from the Marine Actinomycete Salinispora tropica". Organic Letters. 7 (13): 2731–2734. doi:10.1021/ol050901i. PMID 15957933.
Further reading
- Udwary DW, Zeigler L, Asolkar RN, et al. (June 2007). "Genome sequencing reveals complex secondary metabolome in the marine actinomycete Salinispora tropica". Proceedings of the National Academy of Sciences of the United States of America. 104 (25): 10376–81. Bibcode:2007PNAS..10410376U. doi:10.1073/pnas.0700962104. PMC 1965521. PMID 17563368.
- Bucarey, S. A.; Penn, K.; Paul, L.; Fenical, W.; Jensen, P. R. (2012). "Genetic Complementation of the Obligate Marine Actinobacterium Salinispora tropica with the Large Mechanosensitive Channel Gene mscL Rescues Cells from Osmotic Downshock". Applied and Environmental Microbiology. 78 (12): 4175–4182. doi:10.1128/AEM.00577-12. ISSN 0099-2240. PMC 3370544. PMID 22492446.
- Thuan, Nguyen Huy; Yamaguchi, Tokutaro; Lee, Joo Ho; Sohng, Jae Kyung (2013). "Characterization of sterol glucosyltransferase from Salinispora tropica CNB-440: Potential enzyme for the biosynthesis of sitosteryl glucoside". Enzyme and Microbial Technology. 52 (4–5): 234–240. doi:10.1016/j.enzmictec.2013.02.004. ISSN 0141-0229. PMID 23540924.
External links
- LPSN
- "Salinispora tropica" at the Encyclopedia of Life
- WORMS entry
- Type strain of Salinispora tropica at BacDive - the Bacterial Diversity Metadatabase
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