Steven N. Goodman

Steven N. Goodman is an American Professor of Epidemiology and Population Health and of Medicine at the Stanford School of Medicine.[1] He has extensively contributed to foundations of scientific and statistical inference within the biosciences, and in 1999 he coined the term "p-value fallacy".[2]

Steven N Goodman
CitizenshipAmerican
EducationAB, Harvard College, Biochemistry, Applied Math (1976)
Alma materHarvard University
New York University
Johns Hopkins School of Public Health;
Known for"Toward Evidence-Based Medical Statistics. 1: The P Value Fallacy, and 2: The Bayes Factor"
AwardsSpinoza Chair in Medicine (2016), National Academy of Medicine (2020)
Scientific career
FieldsMedical Research, Epidemiology, Statistics, Metascience
ThesisEvidence and Clinical Trials (1989)
Doctoral advisorRichard Royall
Other academic advisorsCurt Meinert

He has served extensively on committees and panels of the National Academies of Science, including Health Effects of Agent Orange in Veterans, 2nd update (1999), Immunization Safety Review Committee (2001-2004), Committee on Alternatives to Daubert Standards (2005), Treatment of Post-traumatic Stress Disorder in Veterans (2007), Committee on Ethical and Scientific Aspects in Studying the Safety of Approved Drugs (Co-chair, 2010-2012), and Committee on Strategies for Responsible Sharing of Clinical Trial Data (2015). He was elected to the National Academy of Medicine in 2020. In addition, he was a member since 2012, then Vice-Chair (since 2016) and Chair (since 2019) of the Methodology Committee of the Patient Centered Patient Outcomes Institute (PCORI).

Life

He graduated with an AB (Bachelor of Arts) from Harvard College in 1976, majoring in Biochemistry and Applied Math. He received an MD from New York University in 1981, completed a pediatrics residency at Washington University in St. Lous, qualified as a Pediatrician in 1985, received an MHS, Biostatistics (1987) and a PhD (1989) Epidemiology from Johns Hopkins School of Public Health.

Co-founder and co-director, along with John Ioannidis, of the Meta-Research Innovation Center at Stanford (METRICS). At Stanford, he is the Associate Dean of Clinical and Translational Research. He was chief of the Division of Epidemiology in the Department of Health Research and Policy from 2014 to 2019, at which time it became the Department of Epidemiology and Population Health.

He has made extensive contributions to medical publishing, as a senior associate editor for statistics since 1987 at the Annals of Internal Medicine, and as inaugural Editor-in-Chief of the journal Clinical Trials: Journal of the Society for Clinical Trials (formerly, Controlled Clinical Trials) from 2004 to 2013.

Recognitions

  • Member of the "National Public Health Honor Society". (1989)
  • Myrto Lefkopoulou Distinguished Lecturer, Harvard Dept of Biostatistics (2000)
  • Elected fellow of the "Society for Clinical Trials". (2010)
  • Spinoza Chair in Medicine, University of Amsterdam (2016)
  • Abraham Lilienfeld Award, American College of Epidemiology (2019)
  • Lifetime Fellow, American College of Epidemiology (2019)
  • Chair, PCORI Methodology Committee (2019)
  • Elected member, National Academy of Medicine (2020)

Works

He has made numerous contributions to the methods of clinical research, comparative effectiveness, meta analysis and scientific inference.[3][4][5][6][7][8][9][10][11][12][13][14] in addition to works on scientific evidence.[15][16][17][18][19][20][21][22][23][24][25][26][27][28]

References

  1. "Steven Goodman".
  2. Sellke, Thomas; Bayarri, M. J; Berger, James O (February 2001). "Calibration of ρ Values for Testing Precise Null Hypotheses". The American Statistician. 55 (1): 62–71. doi:10.1198/000313001300339950.
  3. Cornell, J. E., Mulrow, C. D., Localio, R., Stack, C. B., Meibohm, A. R., Guallar, E., Goodman, S. N. (2014). "Random-Effects Meta-analysis of Inconsistent Effects: A Time for Change". Annals of Internal Medicine. 160 (4): 267–270. doi:10.7326/M13-2886. PMID 24727843.CS1 maint: multiple names: authors list (link)
  4. Basch, E., Aronson, N., Berg, A., Flum, D., Gabriel, S., Goodman, S. N., Helfand, M., Ioannidis, J. P., Lauer, M., Meltzer, D., Mittman, B., Newhouse, R., Normand, S., Schneeweiss, S., Slutsky, J., Tinetti, M., Yancy, C. (2012). "Methodological Standards and Patient-Centeredness in Comparative Effectiveness Research The PCORI Perspective". JAMA. 307 (15): 1636–1640. doi:10.1001/jama.2012.466. PMID 22511692.CS1 maint: multiple names: authors list (link)
  5. Goodman, S. N. (2012). "Quasi-random reflections on randomized controlled trials and comparative effectiveness research". Clinical Trials. 9 (1): 22–26. doi:10.1177/1740774511433285. PMID 22334465.
  6. Sox, H. C., Goodman, S. N. (2012). "The Methods of Comparative Effectiveness Research". Annual Review of Public Health. 33: 425–445. doi:10.1146/annurev-publhealth-031811-124610.CS1 maint: multiple names: authors list (link)
  7. Goodman, S., Dickersin, K. (2011). "Metabias: A Challenge for Comparative Effectiveness Research". Annals of Internal Medicine. 155 (1): 61–2. doi:10.7326/0003-4819-155-1-201107050-00010. PMID 21727295.CS1 maint: multiple names: authors list (link)
  8. Luce, B. R., Kramer, J. M., Goodman, S. N., Connor, J. T., Tunis, S., Whicher, D., Schwartz, J. S. (2009). "Rethinking Randomized Clinical Trials for Comparative Effectiveness Research: The Need for Transformational Change". Annals of Internal Medicine. 151 (3): 206–W45. doi:10.7326/0003-4819-151-3-200908040-00126.CS1 maint: multiple names: authors list (link)
  9. Goodman SN, Greenland S (2007). "Assessing the unreliability of the medical literature: A response to "Why most published research findings are false"". Archived from the original on 2012-04-06. Cite journal requires |journal= (help)
  10. Goodman, S. N. (2002). "The mammography dilemma: A crisis for evidence-based medicine?". Annals of Internal Medicine. 137 (5): 363–365. doi:10.7326/0003-4819-137-5_part_1-200209030-00015.
  11. Goodman, S. N., Zahurak, M. L., PIANTADOSI, S. (1995). "SOME PRACTICAL IMPROVEMENTS IN THE CONTINUAL REASSESSMENT METHOD FOR PHASE-I STUDIES". Statistics in Medicine. 14 (11): 1149–1161. doi:10.1002/sim.4780141102.CS1 maint: multiple names: authors list (link)
  12. Goodman, S. N., Berlin, J. A. (1994). "THE USE OF PREDICTED CONFIDENCE-INTERVALS WHEN PLANNING EXPERIMENTS AND THE MISUSE OF POWER WHEN INTERPRETING RESULTS". Annals of Internal Medicine. 121 (3): 200–206. doi:10.7326/0003-4819-121-3-199408010-00008.CS1 maint: multiple names: authors list (link)
  13. Goodman, S. N. (1989). "META-ANALYSIS AND EVIDENCE". Controlled Clinical Trials. 10 (2): 188–204. doi:10.1016/0197-2456(89)90030-5. PMID 2666026.
  14. Goodman, S. N., Royall, R. (1988). "EVIDENCE AND SCIENTIFIC-RESEARCH". American Journal of Public Health. 78 (12): 1568–1574. doi:10.2105/ajph.78.12.1568. PMC 1349737. PMID 3189634.CS1 maint: multiple names: authors list (link)
  15. Glass, T. A., Goodman, S. N., Hernán, M. A., Samet, J. M. (2013). "Causal inference in public health". Annual Review of Public Health. 34: 61–75. doi:10.1146/annurev-publhealth-031811-124606. PMC 4079266. PMID 23297653.CS1 maint: multiple names: authors list (link)
  16. Faden, R. R., Kass, N. E., Goodman, S. N., Pronovost, P., Tunis, S., Beauchamp, T. L. (2013). "An Ethics Framework for a Learning Health Care System: A Departure from Traditional Research Ethics and Clinical Ethics". Hastings Center Report. 43: S16-27. doi:10.1002/hast.134. PMID 23315888.CS1 maint: multiple names: authors list (link)
  17. Kass, N. E., Faden, R. R., Goodman, S. N., Pronovost, P., Tunis, S., Beauchamp, T. L. (2013). "The Research-Treatment Distinction: A Problematic Approach for Determining Which Activities Should Have Ethical Oversight". Hastings Center Report. 43: S4–S15. doi:10.1002/hast.133. PMID 23315895.CS1 maint: multiple names: authors list (link)
  18. Mello, M. M., Goodman, S. N., Faden, R. R. (2012). "Ethical Considerations in Studying Drug Safety - The Institute of Medicine Report" (PDF). New England Journal of Medicine. 367 (10): 959–964. doi:10.1056/NEJMhle1207160. PMID 22913661.CS1 maint: multiple names: authors list (link)
  19. Goodman, S. (2011). "Confessions of a chagrined trialist". BMJ Quality & Safety. 20 (Suppl_1): i97–i98. doi:10.1136/bmjqs.2010.046623. PMC 3066790. PMID 21450783.
  20. Goodman, S. N. (2007). "Stopping at nothing? Some dilemmas of data monitoring in clinical trials". Annals of Internal Medicine. 146 (12): 882–887. doi:10.7326/0003-4819-146-12-200706190-00010.
  21. Laine, C., Goodman, S. N., Griswold, M. E., Sox, H. C. (2007). "Reproducible research: Moving toward research the public can really trust". Annals of Internal Medicine. 146 (6): 450–453. doi:10.7326/0003-4819-146-6-200703200-00154.CS1 maint: multiple names: authors list (link)
  22. Goodman, S. N., Sladky, J. T. (2005). "A Bayesian approach to randomized controlled trials in children utilizing information from adults: the case of Guillain–Barre syndrome". Clinical Trials. 2 (4): 305–310. doi:10.1191/1740774505cn102oa.CS1 maint: multiple names: authors list (link)
  23. Goodman, S. N. (2001). "Of P-values and bayes: A modest proposal". Epidemiology. 12 (3): 295–297. doi:10.1097/00001648-200105000-00006.
  24. Goodman, S. N. (1999). "Toward evidence-based medical statistics. 1: The P value fallacy". Annals of Internal Medicine. 130 (12): 995–1004. doi:10.7326/0003-4819-130-12-199906150-00008. PMID 10383371.
  25. Goodman, S. N. (1999). "Toward evidence-based medical statistics. 2: The Bayes factor". Annals of Internal Medicine. 130 (12): 1005–1013. doi:10.7326/0003-4819-130-12-199906150-00019. PMID 10383350.
  26. Goodman, S. N., Berlin, J., Fletcher, S. W., Fletcher, R. H. (1994). "MANUSCRIPT QUALITY BEFORE AND AFTER PEER-REVIEW AND EDITING AT ANNALS OF INTERNAL-MEDICINE". Annals of Internal Medicine. 121 (1): 11–21. doi:10.7326/0003-4819-121-1-199407010-00003. PMID 8198342.CS1 maint: multiple names: authors list (link)
  27. Goodman, S. N. (1993). "P-VALUES, HYPOTHESIS TESTS, AND LIKELIHOOD - IMPLICATIONS FOR EPIDEMIOLOGY OF A NEGLECTED HISTORICAL DEBATE". American Journal of Epidemiology. 137 (5): 485–496. doi:10.1093/oxfordjournals.aje.a116700.
  28. Goodman, S. N. (1992). "A COMMENT ON REPLICATION, P-VALUES AND EVIDENCE". Statistics in Medicine. 11 (7): 875–879. doi:10.1002/sim.4780110705.
  • Esteller, Manel; Garcia-Foncillas, Jesus; Andion, Esther; Goodman, Steven N.; Hidalgo, Oscar F.; Vanaclocha, Vicente; Baylin, Stephen B.; Herman, James G. (2000). "Cancer research: Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents". New England Journal of Medicine. 343 (19): 1350–1354. doi:10.1056/NEJM200011093431901. PMID 11070098.
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