Syntaxin binding protein 3

Syntaxin-binding protein 3 is a protein that in humans is encoded by the STXBP3 gene.[5][6]

STXBP3
Identifiers
AliasesSTXBP3, MUNC18-3, MUNC18C, PSP, UNC-18C, Syntaxin binding protein 3
External IDsOMIM: 608339 MGI: 107362 HomoloGene: 5260 GeneCards: STXBP3
Gene location (Human)
Chr.Chromosome 1 (human)[1]
Band1p13.3Start108,746,674 bp[1]
End108,809,523 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

6814

20912

Ensembl

ENSG00000116266

ENSMUSG00000027882

UniProt

O00186

Q60770

RefSeq (mRNA)

NM_007269

NM_011504

RefSeq (protein)

NP_009200

NP_035634

Location (UCSC)Chr 1: 108.75 – 108.81 MbChr 3: 108.79 – 108.84 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

Syntaxin binding protein 3 has been shown to interact with STX2[7] and STX4.[7][8]

References

  1. GRCh38: Ensembl release 89: ENSG00000116266 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000027882 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Reed GL, Houng AK, Fitzgerald ML (April 1999). "Human platelets contain SNARE proteins and a Sec1p homologue that interacts with syntaxin 4 and is phosphorylated after thrombin activation: implications for platelet secretion". Blood. 93 (8): 2617–26. doi:10.1182/blood.V93.8.2617. PMID 10194441.
  6. "Entrez Gene: STXBP3 syntaxin binding protein 3".
  7. Schraw TD, Lemons PP, Dean WL, Whiteheart SW (August 2003). "A role for Sec1/Munc18 proteins in platelet exocytosis". The Biochemical Journal. 374 (Pt 1): 207–17. doi:10.1042/BJ20030610. PMC 1223584. PMID 12773094.
  8. Widberg CH, Bryant NJ, Girotti M, Rea S, James DE (September 2003). "Tomosyn interacts with the t-SNAREs syntaxin4 and SNAP23 and plays a role in insulin-stimulated GLUT4 translocation". The Journal of Biological Chemistry. 278 (37): 35093–101. doi:10.1074/jbc.M304261200. PMID 12832401.

Further reading

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